... The recent data [1] suggested, that the calcium gradient might be one of the key factors involved in the regulation of the functional states of the Ca2+-ATPase and the Ca2+-channels of Ca2+-store sarcoplasmic reticulum (SR). ... The fluorescent probes pyrene and merocyanine 540 were introduced into the vesicles after loading with various concentrations of calcium (0 mM, 0.3 mM, 1mM, and 3 mM). The protein intrinsic tryptophan fluorescence was also used as a probe [2]. ... 2007 Biophysics dep., ...

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. SDPpred: a tool for prediction of amino acid residues . that determine differences in functional specificity of homologous proteins .

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• SDPpred

... Many protein families contain homologous proteins that have a common biological function but different specificity. Given a multiple sequence alignment of a family divided into specificity groups, SDPpred predicts a set of alignment positions ( SDP, Specificity-Determining Positions ) that determine differences in the functional specificity. ... 2004) Automated selection of positions determining functional specificity of proteins by comparative analysis of orthologous groups in protein families. ...

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• SDPlight
• SDPsite - Algorithm Format requirements

Determination of the size of folding nuclei of protofibrils from the concentration dependence of the rate and lag-time of their formation Oxana V. Galzitskaya, Nikita V. Dovidchenko, Olga M. Selivanova, Maria Yu. ... For insulin and LysPro insulin we have Lrel 2-3, which means that it is definitely an exponential growth scenario. One can roughly define three types of possible mechanisms of exponential growth: growth from the surface, bifurcation, and fragmentation. ...

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• http://mccmb.belozersky.msu.ru/2015/proceedings/abstracts/126.pdf
• http://mccmb.belozersky.msu.ru/2015/proceedings/abstracts/66.pdf
• http://mccmb.belozersky.msu.ru/2015/proceedings/abstracts/142.pdf

Diploma thesis ?Infrared and terahertz pulsed spectroscopy of structural changes of proteins and model systems under the interaction with crown-ether? Spectroscopy of the biological molecules is a very important task of the modern science. Protein molecules are among interesting biological complexes. ... One of the possible mechanisms of this effect is formation of complexes of crown-ether with surface amino groups of protein. ... Supervisors: Doctor of Science, Assoc. ...

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. Set 1: List of species Reference tree . Set 2: List of species Reference tree . Set 3: List of species Reference tree . Set 4: List of species Reference tree . For the set 1 . For the sets 2 4

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• Align tool for DNA-protein complexes

... fix #22 Generate meaningful name for monomers subclasses . ... 1 import base . ... 4 class Monomer ( base . Monomer ): . ... 13 """User defined protein; list of protein_sequences.""" . ... 16 class Sequence ( base . ... 19 class Alignment ( base . ... 22 def muscle_align ( self ): . 23 """ Simple align ths alignment using sequences (muscle) . ... 27 tmp_file = NamedTemporaryFile ( delete = False ) . ... 31 sequences , body = Alignment . ... 40 for monomer in body [ new_sequence ]: . ...

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• allpy: bed32775625a allpy/protein.py
• allpy: b5970add0bd9 allpy/protein.py
• allpy: 4516b474c7b5 allpy/protein.py

... Chaperone-like activity of monomeric human 14-3-3zeta on different protein substrates. ... Members of the 14-3-3 protein family interact with hundreds of different, predominantly phosphorylated, proteins. 14-3-3 dimers are prevalent but exist at the equilibrium with the monomers. ... Since the chaperone-like activity of 14-3-3 monomers has been insufficiently studied, here we have analyzed the effect of 14-3-3zetam on the aggregation of different model proteins. ...

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• Versatility of the small heat shock protein HSPB6 (Hsp20).
• Properties of the monomeric form of human 14-3-3zeta protein and its
• Small heat shock protein Hsp27 prevents heat-induced aggregation of F-actin by

... Polyansky A.A. , Volynsky P.E. , Structural Efremov R.G. , Dynamic . в журнале Advances in protein chemistry and structural biology , издательство Elsevier (United States) , том 83, с. 129-161 DOI . ...

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• Protein Expression and Purification - журнал | ИСТИНА - Интеллектуальная
• Journal of protein chemistry - журнал | ИСТИНА - Интеллектуальная Система
• Protein Engineering, Design and Selection - журнал | ИСТИНА - Интеллектуальная

Home . Database of structures of nucleic acid - protein complexes . ... List of complexes . Pfam families . SCOP families . Interaction classes . ... NPIDB . ... Information on SCOP and Pfam domains detected in protein chains is presented. ... Each family has its own web page with the list of entries that include domains of the family. ... List of SCOP domains occurred in DNA-protein and RNA-protein complexes is organized in tree-like form, according to the SCOP classification. ...

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Электронная библиотека Попечительского совета . ... Kambhampati D. (ed.) - Protein Microarray Technology . ... Название: Protein Microarray Technology . Автор: Kambhampati D. (ed.) . ... In doing so, they also offer a comprehensive overview of microarray surface chemistry, detection technologies, fabrication options for array development, and data analysis of numerous types of protein interactions. ... Электронная библиотека попечительского совета мехмата МГУ , 2004-2016 . ...

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• Reith A.D. - Protein Kinase Protocols :: Электронная библиотека попечительского
• Danilkovitch-Miagkova A,, Leonard E.J. - Macrophage-Stimulating Protein (MSP)
• Newton A.C. - Protein Kinase C Protocols :: Электронная библиотека

... More than 20 years structure and functions of two main proteins of muscle and many other systems of biological motility - myosin and actin, are studied by many different methods. ... C-terminal fragment of a new protein with molecular weight of 210 kDa called p3D2 with 70% homology to human and rat protein kinases has been cloned from the Chinese hamster ovary cultured cells CHO. ... Poglazov B.F. Morphogenesis of T-even bacteriophages. ...

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• Laboratory of protein-nucleic interactions (Russian version)
• Screening protein sequence against PROSITE databank
• Databases

... Сравнение трансмембранных белков с разной структурой . ... спираль . ... TMHMM . sp_P21448_MDR1_CRIGR Length: 1276 # sp_P21448_MDR1_CRIGR Number of predicted TMHs: 11 # sp_P21448_MDR1_CRIGR Exp number of AAs in TMHs: 247.07675 # sp_P21448_MDR1_CRIGR Exp number, first 60 AAs: 12.77622 # sp_P21448_MDR1_CRIGR Total prob of N-in: 0.98442 # sp_P21448_MDR1_CRIGR POSSIBLE N-term signal sequence sp_P21448_MDR1_CRIGR TMHMM2.0 inside 1 47 sp_P21448_MDR1_CRIGR TMHMM2.0 TMhelix 48 70 ...

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• 1ldf ТЛ Glycerol uptake facilitator - Orientations of Proteins in Membranes
• 1OKC ТЛ Mitochondrial ADP/ATP carrier - Orientations of Proteins in Membranes
• Membrane proteins

Roman Sutormin rsutormin@gmail.com Professional experience 05/2013 ґ present: Lawrence Berkeley National Laboratory (Berkeley, CA, USA) Software developer Development of JSON based storage system used for keeping biological data involved in public KBase services. ... 10/2009 ґ 08/2011: Mail.Ru Group (Moscow, Russia), Software developer Support and development of data warehouse (PostgreSQL) and administration web tool (JBoss + GWT) on serverside of MMO game "Allods Online". ... 2013 Jul 1514(1):476. ...

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• http://storage.bioinf.fbb.msu.ru/~roman/Sutormin_CV_aug2013.pdf

The carrier of genetic information and major component of chromatin, DNA, is a densely charged polyanion. Electrostatic interactions between DNA and DNA-packaging proteins contribute decisively to formation of elementary unit of chromatin, the nucleosome, and are also important in chromatin folding into higher-order structures. We investigate condensation of DNA and chromatin and find that electrostatics and polyelectrolyte character of DNA play dominant role in these processes. ...

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• Sequence Design of Copolymers with Special Functional Properties - Chair of
• Научный доклад 26.10.2011
• Selected publications of Kiselyova, Olga Igorevna

Group "Biomedical applications for proteins and enzymes. Pharma Biotechnology" . ... Associate Professor Babusenko E.S. (Protein encapsulation) http://www.muctr.ru/univsubs/infacol/ekolog/faculties/f3 . ... Professor Shvetz V.I. , associate Professor Sorokoumova G.M. (Lipid- based protein delivery systems) http://www.mitht.ru . ... Scryabin Moscow Academy of Veterinary Medicine and Biotechnology, Professor Belousova R.V. (Antiviral action of protein preparations) http://www.mgavm.ru . ...

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• Selected papers
• Genetic and Protein Engineering Group
• Members of Genetic and Protein Engineering Group

... A comparative study of thermodynamic for both natural and artificial RNA/DNA ґ protein complexes would establish bases for a specificity of complex formation. In particular, we have shown that aptamers could be used for a direct measuring of thrombin enzymatic activity in a solution. D 2002 Published by Elsevier Science B.V. Keywords: RNA/DNA ґ protein interactions; Ribosome; SELEX; RNA/DNA aptamers; Thrombin; Enzymatic activity 1. ... The aptamer binds to the protein with Kd = 0.5 nM. ...

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• http://rnp-group.genebee.msu.su/pdfs/febsz.pdf
• http://rnp-group.genebee.msu.ru/pages/pdf/biochem2003.pdf
• http://rnp-group.genebee.msu.ru/pages/pdf/nar2004.pdf

... STRATEGY: Development and application of methods of computer molecular modeling, including combined method of quantum mechanics/ molecular mechanics and modern approaches of quantum chemistry, for properties calculations of photoreceptor proteins and their chromophores . ... AREA: Structure and Dynamics of Atomic-Molecular Systems, Physicochemical Biology . ... AREA: Physicochemical Biology, High Molecular Weight Compounds . ... Research Computing Center (RCC) of Lomonosov Moscow State University . ...

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... BBA ? Protein Structure [ BBA Prot Struct] . Common information . ... no information] . ... since 1967-01-18 till 1981-12-29 . ... Recently was part of [BBA - Enzymology and Biological Oxidation]. Now is part of [BBA - Protein Structure and Molecular Enzymology]. ... Elsevier Science . ... http://www.sciencedirect.com/science/.. ... 1967-01-18 . 1981-12-29 . ... http://www.sciencedirect.com/science/... 1971 . ...

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... SmpB 1 - 2008-12-11 - Main.AndreyGolovin . ... During trans- translation, stalled bacterial ribosomes are rescued by small protein B ( SmpB ) and by transfer-messenger RNA (tmRNA). ... We present evidences that SmpB binds the large and small ribosomal subunits in vivo and in vitro . ... SmpB contacts the large subunit transiently and early during the trans -translational process. The affinity of SmpB for the two ribosomal subunits is modulated by tmRNA in the course of trans -translation. ...

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• SmpB - Projects - TWiki
• SmpB - Projects - TWiki - (printable)
• WebHome - Publications - TWiki