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Knowledge-based generalization of metabolic networks: A n applicational study Anna Zhukova and David James Sherman Inria / UniversitИ Bordeaux 1 / CNRS joint project-team MAGNOME, 351, cours de la LibИration, F-33405 Talence Cedex, France {anna.zhukova, david.sherman}@inria.fr Genome-scale metabolic networks are complex systems that describe thousands of reactions participating in the organism's metabolism. ... That is why the analysis by a human expert is needed during the network refinement process. ...

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