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1. MODx Content Manager
MODx encountered the following error while attempting to parse the requested resource: . PHP Parse Error . PHP error debug . Error: . mysql_connect() [ function.mysql-connect ]: Too many connections . Error type/ Nr.: ... home/biochem/biochem.bio.msu.ru/docs/manager/includes/extenders/dbapi.mysql.class.inc.php . Line: . ... Line 87 source: . ... mysql_pconnect($host, $uid, $pwd) : mysql_connect($host, $uid, $pwd, true))) { . Parser timing . ... PHP: . 0.1065 s . ...
[ Сохраненная копия ]  Ссылки http://www.biochem.bio.msu.ru/rus/news/rus/news/semenov?printable=1 -- 3.0 Кб -- 09.04.2016
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2. MODx Content Manager
MODx encountered the following error while attempting to parse the requested resource: . PHP Parse Error . PHP error debug . Error: . mysql_connect() [ function.mysql-connect ]: Too many connections . Error type/ Nr.: ... home/biochem/biochem.bio.msu.ru/docs/manager/includes/extenders/dbapi.mysql.class.inc.php . Line: . ... Line 87 source: . ... mysql_pconnect($host, $uid, $pwd) : mysql_connect($host, $uid, $pwd, true))) { . Parser timing . ... PHP: . 0.0148 s . ...
[ Сохраненная копия ]  Ссылки http://www.biochem.bio.msu.ru/rus/news/rus/news/133?printable=1 -- 3.0 Кб -- 09.04.2016
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3. MODx Content Manager
MODx encountered the following error while attempting to parse the requested resource: . PHP Parse Error . PHP error debug . Error: . mysql_connect() [ function.mysql-connect ]: Too many connections . Error type/ Nr.: ... home/biochem/biochem.bio.msu.ru/docs/manager/includes/extenders/dbapi.mysql.class.inc.php . Line: . ... Line 87 source: . ... mysql_pconnect($host, $uid, $pwd) : mysql_connect($host, $uid, $pwd, true))) { . Parser timing . ... PHP: . 0.0141 s . ...
[ Сохраненная копия ]  Ссылки http://www.biochem.bio.msu.ru/rus/news/rus/news/360?view=print -- 3.0 Кб -- 09.04.2016
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4. Gating mechanisms of a natural anion channelrhodopsin.
... Gating mechanisms of a natural anion channelrhodopsin. ... Anion channelrhodopsins (ACRs) are a class of light-gated channels recently identified in cryptophyte algae that provide unprecedented fast and powerful hyperpolarizing tools for optogenetics. ... The first mechanism, characterized by slow opening and fast closing of the channel, is regulated by Glu-68. ...
[ Сохраненная копия ]  Ссылки http://www.biochem.bio.msu.ru/publications/publication.php?pubmedID=26578767 -- 4.8 Кб -- 09.04.2016
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5. Low Concentrations of Hydrogen Peroxide Activate the Antioxidant Defense System
... Low Concentrations of Hydrogen Peroxide Activate the Antioxidant Defense System in Human Sperm Cells. ... The effect of low concentrations of hydrogen peroxide (10-100 microM) on sperm motility and on the activity of the sperm enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDS) was investigated. ... Thus, the increase in motile spermatozoa in the presence of low concentrations of hydrogen peroxide can serve as an indicator of normal functioning of the antioxidant defense system in sperm cells. ...
[ Сохраненная копия ]  Ссылки http://www.biochem.bio.msu.ru/publications/publication.php?pubmedID=26555470 -- 4.6 Кб -- 09.04.2016
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6. In Vitro Demonstration of Dual Light-Driven Na(+)/H(+) Pumping by a Microbial
... In Vitro Demonstration of Dual Light-Driven Na(+)/H(+) Pumping by a Microbial Rhodopsin. ... A subfamily of rhodopsin pigments was recently discovered in bacteria and proposed to function as dual-function light-driven H(+)/Na(+) pumps, ejecting sodium ions from cells in the presence of sodium and protons in its absence. ... Therefore, an in vitro system consisting of the purified pigment in the absence of other proteins was needed to assign the putative Na(+) and H(+) transport definitively. ...
[ Сохраненная копия ]  Ссылки http://www.biochem.bio.msu.ru/publications/publication.php?pubmedID=26445445 -- 5.2 Кб -- 09.04.2016
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7. Disruption of Amyloid Prion Protein Aggregates by Cationic Pyridylphenylene
... Disruption of Amyloid Prion Protein Aggregates by Cationic Pyridylphenylene Dendrimers. ... Here, for the first time we report that pH-independent cationic pyridylphenylene dendrimers are able to disrupt amyloid protein aggregates at physiological pH as exemplified by inclusion bodies of ovine prion protein. The results show that exposure of inclusion bodies to the dendrimers leads to its partial disaggregation and release of the nanosize protein-dendrimer complexes. ...
[ Сохраненная копия ]  Ссылки http://www.biochem.bio.msu.ru/publications/publication.php?pubmedID=26445143 -- 4.0 Кб -- 09.04.2016
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8. Culturing of Mouse Mesenchymal Stem Cells on Poly-3-Hydroxybutyrate Scaffolds.
... Culturing of Mouse Mesenchymal Stem Cells on Poly-3-Hydroxybutyrate Scaffolds. ... 2015 Aug;159(4):567-71. doi: 10.1007/s10517-015-3015-5. ... We studied the possibility of long-term culturing of mouse mesenchymal stem cells on a porous scaffold made of biocompatible polymer poly-3-hydroxybutyrate. ... Culturing on the scaffold did not change surface phenotype of cells. 3D poly-3-hydroxybutyrate scaffolds are appropriate substrate for long-term culturing of mesenchymal stem cells. ...
[ Сохраненная копия ]  Ссылки http://www.biochem.bio.msu.ru/publications/publication.php?pubmedID=26388561 -- 4.1 Кб -- 09.04.2016
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9. Binding of ouabain and marinobufagenin leads to different structural changes in
... Binding of ouabain and marinobufagenin leads to different structural changes in Na,K-ATPase and depends on the enzyme conformation. ... We have shown that both CTS inhibit activity of Na,K-ATPase with the same Ki values, but binding of ouabain is sensitive to the conformation of Na,K-ATPase while binding of marinobufagenin is not. Furthermore, binding of ouabain and marinobufagenin results in different structural changes in Na,K-ATPase. ...
[ Сохраненная копия ]  Ссылки http://www.biochem.bio.msu.ru/publications/publication.php?pubmedID=26297827 -- 4.2 Кб -- 09.04.2016
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10. NEUROSCIENCE. Natural light-gated anion channels: A family of microbial
... NEUROSCIENCE. Natural light-gated anion channels: A family of microbial rhodopsins for advanced optogenetics. ... We describe anion channel rhodopsins (ACRs), a family of light-gated anion channels from cryptophyte algae that provide highly sensitive and efficient membrane hyperpolarization and neuronal silencing through light-gated chloride conduction. ... Natural ACRs provide optogenetic inhibition tools with unprecedented light sensitivity and temporal precision. ...
[ Сохраненная копия ]  Ссылки http://www.biochem.bio.msu.ru/publications/publication.php?pubmedID=26113638 -- 4.3 Кб -- 09.04.2016
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11. Critical role of the alpha1-Na(+), K(+)-ATPase subunit in insensitivity of
... Critical role of the alpha1-Na(+), K(+)-ATPase subunit in insensitivity of rodent cells to cytotoxic action of ouabain. ... In 24, 3 muM ouabain triggered the death of all types of human cells used in this study. ... Overall, our results, demonstrate that the drastic differences in cytotoxic action of ouabain on human and rodent cells are caused by unique features of alpha1S/alpha1R-Na(+), K(+)-ATPase, rather than by any downstream CTS-sensitive/resistant components of the cell death machinery. ...
[ Сохраненная копия ]  Ссылки http://www.biochem.bio.msu.ru/publications/publication.php?pubmedID=26067145 -- 5.2 Кб -- 09.04.2016
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12. Characterization of endogenously circulating IGFBP-4 fragments-Novel biomarkers
... Characterization of endogenously circulating IGFBP-4 fragments-Novel biomarkers for cardiac risk assessment. ... BACKGROUND: Recent findings show that circulating N- and C-terminal fragments of IGF-binding protein-4 (NT-IGFBP-4 and CT-IGFBP-4) can be utilized as biomarkers for cardiac risk assessment in acute coronary syndrome (ACS) patients. ... However, properties of the endogenous IGFBP-4 fragments that could influence the performance of the immunoassays were still not investigated. ...
[ Сохраненная копия ]  Ссылки http://www.biochem.bio.msu.ru/publications/publication.php?pubmedID=26025773 -- 5.5 Кб -- 09.04.2016
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13. Structural basis for the NAD binding cooperativity and catalytic
... Structural basis for the NAD binding cooperativity and catalytic characteristics of sperm-specific glyceraldehyde-3-phosphate dehydrogenase. ... We exploited mammalian glyceraldehyde-3-phosphate dehydrogenase as a model protein and examined the structural basis of the NAD(+) cooperative binding exhibited by its homologous isoenzymes: the somatic enzyme (GAPD) and the recombinant sperm-specific enzyme (dN-GAPDS). ...
[ Сохраненная копия ]  Ссылки http://www.biochem.bio.msu.ru/publications/publication.php?pubmedID=25936797 -- 4.5 Кб -- 09.04.2016
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14. Structural basis for regulation of stability and activity in
... Structural basis for regulation of stability and activity in glyceraldehyde-3-phosphate dehydrogenases. Differential scanning calorimetry and molecular dynamics. ... Tissue specific isoforms of human glyceraldehyde-3-phosphate dehydrogenase, somatic (GAPD) and sperm-specific (GAPDS), have been reported to display different levels of both stability and catalytic activity. Here we apply MD simulations to investigate molecular basis of this phenomenon. ...
[ Сохраненная копия ]  Ссылки http://www.biochem.bio.msu.ru/publications/publication.php?pubmedID=25869789 -- 5.1 Кб -- 09.04.2016
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15. Attempt to optimize some properties of fluorescent chimeras of human small heat
... Attempt to optimize some properties of fluorescent chimeras of human small heat shock protein HspB1 by modifying linker length and nature. ... Chimerical proteins consisting of enhanced yellow fluorescent protein (EYFP) connected by linkers of different length and nature to the N-terminal end of small heat shock protein HspB1 were obtained and characterized. ... Long flexible linkers should be used to obtain fluorescent chimeras with chaperone-like properties similar to those of the wild-type HspB1....
[ Сохраненная копия ]  Ссылки http://www.biochem.bio.msu.ru/publications/publication.php?pubmedID=25754041 -- 5.1 Кб -- 09.04.2016
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16. Upstream open reading frames regulate translation of the long isoform of SLAMF1
... Upstream open reading frames regulate translation of the long isoform of SLAMF1 mRNA that encodes costimulatory receptor CD150. ... More than 40% of human genes contain upstream open reading frames (uORF) in their 5'-untranslated regions (5'-UTRs) and at the same time express at least one truncated mRNA isoform containing no uORF. ... CD150 is a member of the CD2 superfamily, a costimulatory lymphocyte receptor, a receptor for measles virus, and a microbial sensor on macrophages. ...
[ Сохраненная копия ]  Ссылки http://www.biochem.bio.msu.ru/publications/publication.php?pubmedID=25716736 -- 5.1 Кб -- 09.04.2016
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17. Low-temperature (77 K) phosphorescence of triplet chlorophyll in isolated
... Low-temperature (77 K) phosphorescence of triplet chlorophyll in isolated reaction centers of photosystem II. ... 2015 Aug;125(1-2):43-9. doi: 10.1007/s11120-015-0105-1. Epub 2015 Feb 25. ... The phosphorescence intensity strongly depends upon the redox state of RCs. The data suggest that the phosphorescence signal originates from the chlorophyll triplet state populated via charge recombination in the radical pair [Formula: see text]. ...