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... Nevertheless, in mammals and in other intron-rich organisms, many of the SSs often involve nonconsensus (Nc), rather than consensus (Cn), nucleotides, and beyond the two critical nucleotides, the SSs are not perfectly conserved between species. ... GBE exon intron exon intron exon Acceptor splice site Consensus Nonconsensus -24-23-22 -21-20-19-18-17-16 -15-14-13-12 -11-10 -9 -8 -7 -6 -5 -4 -3 -2 -1 +1 Position number -3 -2 Donor splice site -1 +1 +2 +3 Position number +4 +5 +6 FIG.1.- ...

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205. http://dfgm.math.msu.su/files/ivanov-tuzhilin/Lecture_Notes.pdf