Документ взят из кэша поисковой машины. Адрес оригинального документа : http://www.mce.biophys.msu.ru/archive/doc15511/doc.pdf
Дата изменения: Wed Oct 17 17:11:42 2007
Дата индексирования: Mon Oct 1 21:36:43 2012
Кодировка:
C : ( ) . . , - . ., . . (, ) , , , , .. , . , , . , . , , , , . , , . , «» «» , . . , .


5. Part 5. Computer technologies

, . , , , , . , , , , , - . . , . , . , ( ) , , . , tb te -- () . , , . [tb , te ] [ 0, T ] , T = te - tb . , T .

(). [tb , te ] , -

H = {H i } , i = 1, n . H i

Ti . H , , , m .
388


. . . -- -- 2005, . 2, . 387 ­ 389 Shakin V. V. et. al. -- MCE -- 2005, vol. 2, p. 387 ­ 389
i i p1i , p2 ,K , pm , i = 1, n , pij j -

i - H i . p j i

, , [0, Ti ] . T ji p ij p j (t ) , t T ji = {t ij ,1 , t ij ,2 ,K , t ij ,k } . p j , - [0, Ti ] . Pj . H i H
i

i

i


fi : [0, Ti ] R m в [0, Ti ] ,
i fi (t ) = ( Pi (t ), P2i (t ),K , Pm (t ), t ) 1

(1)

, , (1) t , , . m [0, Ti ] . , , , . . i Pj H . j j j j Pmin Pmax : Pmin = min Pji , Pmax = max Pji .
i
i

P , -. j Popt . , ,
389

i j


5. Part 5. Computer technologies

-- Popt = 36, 6 .
o

Pj (t )
P j (t ) =
i j Pji (t ) - Pop j opt t j j max( P - Pmin , Pmjax - Popt )

i

.
i

P j , Pji (t ) . , , , , . . Ti H i H . Tmax H Tmin , .. Tmax = max{Ti } , Tmin = min{Ti } .
i i

Ti , :
Ti = Ti - Tmin . Tmax - Tmin

, f i f
f i :[0, T i ] [-1,1]m в [0, T i ] , T i [0,1] .
i

, H i H , . , , . f i (t ) , t [0, T i ] si (t ) , , f i (t ) t .
390


. . . -- -- 2005, . 2, . 387 ­ 391 Shakin V. V. et. al. -- MCE -- 2005, vol. 2, p. 387 ­ 391

, ti ( s ) , si (t ) . ti ( s ) t i ( s ) , s [0,1] :
t i ( s ) = ti ( s S
i ax

) , S

i ax

= si (T i ) .

, , f i (t ) . , f i (t ) f i
f i :[0,1] [ -1,1]m ,
f i ( s ) = ( P1 (t i ( s )), P 2 (t i ( s )),K , P m (t i ( s ))) , s [0,1]
i i i

(2)

CH H i H , (2).
f , g = ( P1 (t f ( s)) P1 (t g ( s )) + K + P m (t f ( s )) P m (t g ( s )))ds
0 1 f g f g

,
|| f ||= f , f , ( f , g ) =|| f - g || .

, , , .

391


5. Part 5. Computer technologies

( [1]) . ( p1 , p2 ,K p12 )
1 ( p1 ) 2 ( p2 ) 3 ( p3 ) 4 ( p4 ) 5 ( p5 ) 6 ( p6 ) 7 ( p7 ) 8 ( p8 ) 9 ( p9 ) 10 ( p10 ) 11 ( p11 ) 12 ( p12 ) B-

-- t «» . ­ . , , . 0, 1 .. [0, T ] .
04.04.1997 0 05.04.1997 1 06.04.1997 2 ... ... 21.01.1998 26

392


. . . -- -- 2005, . 2, . 387 ­ 393 Shakin V. V. et. al. -- MCE -- 2005, vol. 2, p. 387 ­ 393

­ Temp (t ) , t [0, T ] , . , , 1. , .
0 36,6 1 36,7 2 36,6 ... ... 26 36,8

-- Tr (t ) , t [0, T ] -- , . «» 9 10 , Tr 10 /. , Tr . , , . tb te , . «»
9



0 295,0

2 295,0

18 186,0

21 227,0

24 170,0

26 170,0

-- Le(t ) , t [0, T ] -- , . «» 9 10 , Le 10 /. «» Le , 9

393


5. Part 5. Computer technologies

[tb , te ] . «»
0 12,8 2 12,8 18 1,3 21 1,9 24 2,4 26 2,4

, , , . . Popt


36, 6

o

250 109 /
6 109 /

Matlab. , . , SPSS. , . , (. 1).

394


. . . -- -- 2005, . 2, . 387 ­ 395 Shakin V. V. et. al. -- MCE -- 2005, vol. 2, p. 387 ­ 395

. 1

, . , , . , , , , , , - , (, ). , , , . , .
395


5. Part 5. Computer technologies

, « », , . , () , . « ». , . « » , . , . , [1]. , . , -- .
04-01-00401-a.

: 1. Nikita Shklovskiy-Kordi. Multimedia Case History as a Tool for Management of Cancer Patients and Clinical Trials. UICC Abstracts. -- Dublin, 2004. 2. Vsevolod V. Shakin, et al. Life Support Systems in Medicine and Biology. ORM-2004 -- Operations Research International Conference, Proceedings. -- Moscow, Dorodnicyn Computing Center of the Russian Academy of Sciences, 2004. 3. .. . -- .: «», 1981.

396


. . . -- -- 2005, . 2, . 387 ­ 397 Shakin V. V. et. al. -- MCE -- 2005, vol. 2, p. 387 ­ 397

DECISION SUPPORT SYSTEM USING MULTIMEDIA CASE HISTORY: QUANTITATIVE COMPARISON AND MULTIVARIATE STATISTICAL ANALYSIS (TOWARDS UNIFIED WHO LANGUAGE IN THE SUBJECT AREA) Shakin V. V. , Shklovskiy-Kordi N. E., Ptashko G. O. (Russia, Moscow) Decision Support System, or DSS, for case-to-case and case-tocluster comparative and multivariate statistical analysis based on modeling and generalization of verified clinical information on individual patients. The DSS makes individual MMCH data pair-wise comparable using normalization procedures in individual time-andsubspace time domain and interpolation techniques for multimedia data. All that serves as background for a Unified Language to meet needs of WHO in quantitative description, comparison and generalization of individual patients' patterns.

397