Современные проблемы химии
Курсы по выбору на английском языке
Курс по выбору
"Development of new drugs: legal and economic aspects"
Лекторы
Куркин А.В., доц., к.х.н.,; Андреа Алтиери, н.с., к.х.н.,; Зефирова О.Н. , проф., д.х.н.
Аннотация курса
The Pharma industry that attracts so much attention it is very surprising how little is known about the inner work. This world is a complex, nonlinear, and based on several different value systems. The scope of this tutorial is to bring an insight in the Pharma World and to give listeners knowledge of legal and economic aspects of the Drug Discovery process. After a bring introduction we are going to tackle different pragmatic aspect of the drug discovery pipeline, ranging from science, timeline and economic. A brief outline of the lectures are reported below (the tutorial program may be subjected to variations/amendments before the tutorial starts) Lecture 1: Intro to the Drug Discovery Business World - R&D productivity & Drug Discovery Pipeline
Lecture 2: Target Selection & Validation
Lecture 3: Hit Generation & Compound Libraries
Lecture 4: Fragment Based Drug Discovery Approach
Lecture 5: H2L & Optimization - part 1 (IP, activity + selectivity)
Lecture 6: H2L & Optimization - part 2 (ADME + tox:)
Lecture 7: CNS Drug Discovery
Lecture 8: in vitro studies
Lecture 9: in vivo studies & GMP
Lecture 10: Business Opportunities in the DD world - The CRO adventure
