Документ взят из кэша поисковой машины. Адрес оригинального документа : http://www.chem.msu.ru/rus/chair/org_w/seminars/Rubin%2019.09.2014.pdf Дата изменения: Tue Jan 27 11:48:11 2015 Дата индексирования: Sun Apr 10 23:47:18 2016 Кодировка:

(M

ICHAEL

RUB

IN

)

Diastereo- and Enantioselective Transition-Metal Catalyzed Additions to Cyclopropenes (- , ).
Innovative synthetic approaches towards highly functionalized densely substituted cyclopropanes via transition metal-catalyzed additions of various entities across highly reactive strained double bonds of cyclopropene precursors will be demonstrated. These will include discussion on highly diastereoselective hydrometallation (hydrostannation, hydrosilylation) reactions governed by either steric factors of directed by appropriate functional groups. Also, possibility for highly efficient dimetallation, hydrophosphorylation and hydrophosphinylation reactions will be demonstrated. Designing of novel enantioselective processes will be illustrated as well, including asymmetric hydroboration, hydrostannation and hydroformylation methodologies. Plausible mechanistic rationales will be provided and our Insights on the origins of asymmetric induction will be discussed. . (, ), , . , , . , - , , . . , ( ). (. ). 1989 1994 .


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