|
L. O. Lokhova, D. A. Polyanina, M. K. Beklemishev
Molecular imprinting of
penicillin V in polyelectrolyte layers deposited onto a track-etched membrane
Abstract
Polyethylene
terephthalate track-etched membranes have been modified by deposition of
polyallylamine hydrochloride and polyacrylic acid monolayers from 91–96% (vol.)
ethanol with and without penicillin V. Sorption and diffusion of penicillin V
is higher for the membranes modified in the presence of this compound (the
imprinted ones), which evidences the formation of molecular imprints of the
template in the polyelectrolyte layer. The imprints are formed if the
polyelectrolytes are deposited onto the membrane from a solution of ionic
liquid (butylmethylimidazolium tetrafluoroborate). Sorption of foreign
compounds on imprinted and non-imprinted membranes does not differ, which
confirms the formation of selective molecular imprints of penicillin V.
Key words: molecular
imprinting, track-etched membranes, polyelectrolytes, penicillin V, sorption,
diffusion.
Copyright (C) Chemistry Dept., Moscow State University, 2002
|
|
