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Pfam

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Protein Family Data Bank, Pfam



Domain Structure of the Protein DNA Gyrase B in E.coli

Ill.1 The Protein DNA gyrase subunit b (ec 5.99.1.3)




Table1. Pfam Identificator, short name and full name of each domain contained in DNA Gyrase B





Ill2. 3D Structure of DNA Gyrase B [PDB ID:1ei1]




Highlightening the Subfamily to which belongs the N-end Domain of DNA Gyrase B in E.coli

Histidine Kinase-, DNA Gyrase- i HSP90- like ATPase (HATPase)

This family represents structural related ATP domains of HistidineKinase, DNA Gyrase and HDP90. It forms structural complexes with other families present in the Pfam data base. The family is found in several ATP binding proteins, as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins.



Table2. Distribution of the Domain HATPase in different Taxons
Totally 8252 proteins containing the domain HATPase C are known. This domain is most frequently found in multipledomain proteins. Analyzing the results of the results leads to the conclusion that the domain does not exist as a singledomain protein. There are 8 known domain architectures (21 different proteins [see *]) were the domain is duplicated.


* 1 protein with HisKA, HATPase_c, Response_reg, HisKA, HATPase_c, Response_reg architecture- Q95PI1_DICDI [ dictyostelium discoideum (slime mold)] double histidine kinase dhkd, 1 protein with 7TMR-DISM_7TM, HisKA, HATPase_c, Response_reg, His_kinase, HATPase_c architecture Q9KBB5_BACHD [ bacillus halodurans] bh2013 protein, 2 proteins with HATPase_c, HisKA, HATPase_c, Response_reg architecture Q6H037_FREDI [ fremyella diplosiphon (calothrix pcc 7601)] putative two component hybrid sensor kinase, 2 proteins with HisKA, HATPase_c, Response_reg, HisKA, HATPase_c architecture Q8F425_LEPIN [ leptospira interrogans] two-component hybrid sensor and regulator, 3 proteins with PAS, HisKA, HATPase_c, Response_reg, PAS, HisKA, HATPase_c architecture Q8KIY1_PSEME [ pseudomonas mendocina] bzip histidine kinase, 4 proteins with HisKA, HATPase_c, Response_reg, His_kinase, HATPase_c architecture Q5WAT9_BACSK [ bacillus clausii (strain ksm-k16)] hypothetical protein, 4proteins with PAS, HisKA, HATPase_c, Response_reg, HisKA, HATPase_c architecture Q5X3F2_LEGPA [ legionella pneumophila (strain paris)] sensor histidine kinase, 5 proteins with HisKA, HATPase_c, Response_reg, PAS, HisKA, HATPase_c architecture. O30988_PSEFL [ pseudomonas fluorescens] hybrid histidine kinase homolog

See Original Protocol on this page

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© Santesson Elly, 2004