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UNIVERSITY OF MICHIGAN | COLLEGE OF PHARMACY
| MOSBERG LAB

PDB ID or protein name

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* ABOUT OPM
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* LIPID COMPOSITION ATLAS

* Protein Classification

* *Types* (4 types)
* *Classes* (11 classes)
* *Superfamilies* (211 superfamilies)
* *Families* (309 families)
* *Species* (298 species)
* *Localization* (22 types)
* *All proteins in OPM* (902 entries)


* Protein Links

* PDB Sum ,
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* OCA ,
* MMDB


2ZW3 ТЛ Connexin 26 gap junction channel (beta-2 protein)

2zw3 ТЛ Connexin 26 gap junction channel (beta-2 protein)

Magnify 2zw3 ТЛ Connexin 26 gap junction channel (beta-2 protein)Enlarged
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/Topology in Eukaryotic plasma membrane/
Topology *extracellular side*
*cytoplasmic side*

* /Type:/ 1. Transmembrane (2 classes)
* /Class:/ 1.1. Alpha-helical transmembrane
(57 superfamilies)
* /Superfamily:/ 1.1.52. Gap junction-forming connexin
(1 family) 1.A.24 (TCDB)

* /Family:/ 1.1.52.01. Connexin (1
protein) 1.A.24 (TCDB)
* /Species:/ /Spodoptera frugiperda frugiperda>/ (1 protein)
* /Localization:/ Eukaryotic plasma membrane
(199
proteins)

2zw3 ТЛ Connexin 26 gap junction channel (beta-2 protein)
*Hydrophobic Thickness* 32.5 ТБ 1.3 У?
*Tilt Angle* 0 ТБ 1ТА
*Ю?G_transfer * -170.5 kcal/mol
*Links to 2zw3* PDB Sum
,
SCOP , MSD
, OCA
, MMDB
, Dali

*Topology* subunit A (N-terminus cytoplasmic)
*Resolution* 3.50 У?
*Related PDB Sum entries* 1txh
,
1xir


*Number of TM Secondary Structures* 24

6 transmembrane subunits
*A* - Tilt: 20ТА - Segments: 1( 22- 45), 2( 73- 91), 3( 137- 157), 4(
187- 211)
*B* - Tilt: 19ТА - Segments: 1( 22- 45), 2( 73- 91), 3( 137- 157), 4(
187- 211)
*C* - Tilt: 19ТА - Segments: 1( 22- 45), 2( 73- 91), 3( 137- 157), 4(
187- 211)
*D* - Tilt: 19ТА - Segments: 1( 22- 45), 2( 73- 91), 3( 137- 157), 4(
187- 211)
*E* - Tilt: 19ТА - Segments: 1( 22- 45), 2( 73- 91), 3( 137- 157), 4(
187- 211)
*F* - Tilt: 19ТА - Segments: 1( 22- 45), 2( 73- 91), 3( 137- 157), 4(
187- 211)


Copyright Т? 2005- Andrei Lomize , Mikhail Lomize
and Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA
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