In recent years the emergence of new man-made environmental factors led to adverse (resulting in negative economic and social consequences) changes in the human population structure. This results in significant changes in the population structure, namely the reduction and disappearance of certain groups of the population (carriers of certain genetic, phenotypic, economic and cultural characteristics). Therefore, there is an irreversible loss of evolutionarily significant individual genes carriers and entire groups adapted to living in certain conditions. Gene variants that now seem useless or even unfavorable may be necessary in the future of humanity. An example is the one of chemokine receptors defective gene carriers? resistance to human immunodeficiency virus.

Therefore it is extremely important to create a representative human biological material cryocollection which will contain both rare genomic embodiments and presently widespread in the population genomic variants, including comprehensive descriptions of the donor material. In forming the basis of such cryocollection it is necessary to analyze composition of needed to fix and preserve medical and biological, anthropological, psycho-physiological, environmental, and other significant human traits and characteristics, including molecular-biological and morphological characteristics of the material. Previously, such a comprehensive systematic characterization of the donor was not carried out because of low area elaboration, undeveloped instrumental methods of quantitative characteristics obtaining and data large number analysis complexity. Attainability of the problem solving and obtaining the anticipated results within this area is guaranteed by significant technological advance, material and human resources of the Moscow State University faculties, which will be involved in the works execution.