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S. A. Yamashkin, EA. Oreshkina, M. A. Yurovskaya
About the possibility of using of
5-, 6-amino-2,3,7-trimethyl-, 1,2,3,7-tetramethylindoles in synthesis of
trifluoromethylpyrroloquinolones
Abstract
It was showed that 5-, 6-amino-2,3,7-trimethyl- and
5-, 6-amino-l,2,3,7-tetramethylindoles react with the
trifluoroethylacetoacetat, in boiling benzene with formation corresponding
amides, wich cyclizate into corresponding trifluoromethylpyrroloquinolones in
trifluoroacetic acid, exepting amide from 5-amino-l,2,3,7-tetramethylindole,
wich don’t cyclizate by the long boiling in trifluoroacetic acid.
Copyright (C) Chemistry Dept., Moscow State University, 2002
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