Документ взят из кэша поисковой машины. Адрес оригинального документа : http://monkey.belozersky.msu.su/npidb/pdb/pdb_new/stride/2ko0.std.txt Дата изменения: Tue Jan 18 15:18:30 2011 Дата индексирования: Fri Feb 11 21:20:30 2011 Кодировка:

REM -------------------------------------------------------------------- 2KO0
REM 2KO0
REM STRIDE: Knowledge-based secondary structure assignment 2KO0
REM Please cite: D.Frishman & P.Argos, Proteins 23, 566-579, 1995 2KO0
REM 2KO0
REM Residue accessible surface area calculation 2KO0
REM Please cite: F.Eisenhaber & P.Argos, J.Comp.Chem. 14, 1272-1280, 1993 2KO0
REM F.Eisenhaber et al., J.Comp.Chem., 1994, submitted 2KO0
REM 2KO0
REM ------------------------ General information ----------------------- 2KO0
REM 2KO0
HDR TRANSCRIPTION/DNA 08-SEP-09 2KO0 2KO0
CMP MOL_ID: 1; 2KO0
CMP MOLECULE: THAP DOMAIN-CONTAINING PROTEIN 1; 2KO0
CMP CHAIN: A; 2KO0
CMP FRAGMENT: UNP RESIDUES 1-82; 2KO0
CMP ENGINEERED: YES; 2KO0
CMP MUTATION: YES; 2KO0
CMP MOL_ID: 2; 2KO0
CMP MOLECULE: RRM1; 2KO0
CMP CHAIN: B; 2KO0
CMP ENGINEERED: YES; 2KO0
CMP OTHER_DETAILS: SPECIFIC THAP1 BINDING SEQUENCE ELEMENT 2KO0
CMP FOUND IN THE RRM1 GENE PROMOTER; 2KO0
CMP MOL_ID: 3; 2KO0
CMP MOLECULE: ZINC ION; 2KO0
CMP CHAIN: C; 2KO0
CMP ENGINEERED: YES; 2KO0
CMP OTHER_DETAILS: SPECIFIC THAP1 BINDING SEQUENCE ELEMENT 2KO0
CMP FOUND IN THE RRM1 GENE PROMOTER 2KO0
SRC MOL_ID: 1; 2KO0
SRC ORGANISM_SCIENTIFIC: HOMO SAPIENS; 2KO0
SRC ORGANISM_COMMON: HUMAN; 2KO0
SRC ORGANISM_TAXID: 9606; 2KO0
SRC GENE: THAP1; 2KO0
SRC EXPRESSION_SYSTEM: ESCHERICHIA COLI; 2KO0
SRC EXPRESSION_SYSTEM_TAXID: 562; 2KO0
SRC EXPRESSION_SYSTEM_STRAIN: BL21; 2KO0
SRC EXPRESSION_SYSTEM_VARIANT: DE3; 2KO0
SRC EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; 2KO0
SRC EXPRESSION_SYSTEM_VECTOR: PET26; 2KO0
SRC MOL_ID: 2; 2KO0
SRC SYNTHETIC: YES; 2KO0
SRC OTHER_DETAILS: DNA SYNTHESIS; 2KO0
SRC MOL_ID: 3; 2KO0
SRC SYNTHETIC: YES; 2KO0
SRC OTHER_DETAILS: DNA SYNTHESIS 2KO0
AUT S.CAMPAGNE,V.GERVAIS,O.SAUREL,A.MILON 2KO0
REM 2KO0
REM -------------------- Secondary structure summary ------------------- 2KO0
REM 2KO0
CHN /data/npidb/pdb/pdb_new/all/pdb2ko0.pdb A 2KO0
REM 2KO0
REM . . . . . 2KO0
SEQ 1 MVQSCSAYGCKNRYDKDKPVSFHKFPLTRPSLCKEWEAAVRRKNFKPTKY 50 2KO0
STR TTTT TTTT TTTTT EEE TTTTHHHHHHHHHHH TTTT TTT 2KO0
REM 2KO0
REM . . . 2KO0
SEQ 51 SSICSEHFTPDSFKRESNNKLLKENAVPTIFLELVPR 87 2KO0
STR TEEEGGG GGGTTTTTTTTT TTTT TTTT 2KO0
REM 2KO0
REM 2KO0
REM 2KO0
LOC AlphaHelix PRO 30 A VAL 40 A 2KO0
LOC 310Helix SER 55 A HIS 57 A 2KO0
LOC 310Helix PRO 60 A SER 62 A 2KO0
LOC Strand PHE 22 A LYS 24 A 2KO0
LOC Strand SER 52 A CYS 54 A 2KO0
LOC TurnIV MET 1 A SER 4 A 2KO0
LOC TurnII ALA 7 A CYS 10 A 2KO0
LOC TurnI ASP 15 A LYS 18 A 2KO0
LOC TurnVIII LYS 16 A PRO 19 A 2KO0
LOC TurnI PRO 26 A ARG 29 A 2KO0
LOC TurnIV LEU 27 A PRO 30 A 2KO0
LOC TurnIV ARG 42 A PHE 45 A 2KO0
LOC TurnI THR 48 A SER 51 A 2KO0
LOC TurnIV PHE 63 A GLU 66 A 2KO0
LOC TurnI LYS 64 A SER 67 A 2KO0
LOC TurnIV SER 67 A LYS 70 A 2KO0
LOC TurnIV ASN 68 A LEU 71 A 2KO0
LOC TurnI LYS 73 A ALA 76 A 2KO0
LOC TurnIV PRO 78 A PHE 81 A 2KO0
REM 2KO0
REM --------------- Detailed secondary structure assignment------------- 2KO0
REM 2KO0
REM |---Residue---| |--Structure--| |-Phi-| |-Psi-| |-Area-| 2KO0
ASG MET A 1 1 T Turn 360.00 157.03 55.0 2KO0
ASG VAL A 2 2 T Turn -98.32 30.06 95.3 2KO0
ASG GLN A 3 3 T Turn -110.46 -59.81 146.2 2KO0
ASG SER A 4 4 T Turn -178.04 154.02 6.2 2KO0
ASG CYS A 5 5 C Coil -77.22 169.50 0.3 2KO0
ASG SER A 6 6 C Coil -73.74 3.92 1.1 2KO0
ASG ALA A 7 7 T Turn -79.54 -174.38 0.2 2KO0
ASG TYR A 8 8 T Turn -104.13 94.57 45.9 2KO0
ASG GLY A 9 9 T Turn 96.52 -0.48 49.2 2KO0
ASG CYS A 10 10 T Turn -80.30 72.85 10.8 2KO0
ASG LYS A 11 11 C Coil -85.96 46.84 159.4 2KO0
ASG ASN A 12 12 C Coil -85.72 48.90 57.8 2KO0
ASG ARG A 13 13 C Coil -32.00 128.78 128.9 2KO0
ASG TYR A 14 14 C Coil -27.37 106.77 106.4 2KO0
ASG ASP A 15 15 T Turn -132.06 105.40 49.4 2KO0
ASG LYS A 16 16 T Turn -56.20 -25.73 175.5 2KO0
ASG ASP A 17 17 T Turn -66.43 -34.31 125.1 2KO0
ASG LYS A 18 18 T Turn -88.46 144.49 58.0 2KO0
ASG PRO A 19 19 T Turn -80.68 76.51 129.0 2KO0
ASG VAL A 20 20 C Coil -147.93 146.13 23.1 2KO0
ASG SER A 21 21 C Coil -121.66 161.15 39.7 2KO0
ASG PHE A 22 22 E Strand -108.09 160.60 19.9 2KO0
ASG HIS A 23 23 E Strand -156.80 177.35 25.9 2KO0
ASG LYS A 24 24 E Strand -111.35 166.74 128.3 2KO0
ASG PHE A 25 25 C Coil -60.55 155.96 8.4 2KO0
ASG PRO A 26 26 T Turn -70.03 75.26 2.9 2KO0
ASG LEU A 27 27 T Turn -67.40 -24.54 78.3 2KO0
ASG THR A 28 28 T Turn -91.57 7.30 108.9 2KO0
ASG ARG A 29 29 T Turn -141.86 60.41 95.4 2KO0
ASG PRO A 30 30 H AlphaHelix -48.37 -58.98 83.1 2KO0
ASG SER A 31 31 H AlphaHelix -50.53 -46.77 88.4 2KO0
ASG LEU A 32 32 H AlphaHelix -66.29 -36.03 2.9 2KO0
ASG CYS A 33 33 H AlphaHelix -60.95 -36.29 4.4 2KO0
ASG LYS A 34 34 H AlphaHelix -67.77 -31.73 145.8 2KO0
ASG GLU A 35 35 H AlphaHelix -74.04 -18.37 68.5 2KO0
ASG TRP A 36 36 H AlphaHelix -63.14 -30.56 2.4 2KO0
ASG GLU A 37 37 H AlphaHelix -63.55 -35.01 57.9 2KO0
ASG ALA A 38 38 H AlphaHelix -64.38 -24.88 77.6 2KO0
ASG ALA A 39 39 H AlphaHelix -84.45 -25.94 15.0 2KO0
ASG VAL A 40 40 H AlphaHelix -89.46 49.25 5.5 2KO0
ASG ARG A 41 41 C Coil -64.12 14.96 96.0 2KO0
ASG ARG A 42 42 T Turn -105.68 150.14 97.1 2KO0
ASG LYS A 43 43 T Turn -57.24 -41.69 206.4 2KO0
ASG ASN A 44 44 T Turn -77.11 63.07 83.8 2KO0
ASG PHE A 45 45 T Turn -69.43 117.32 68.8 2KO0
ASG LYS A 46 46 C Coil -68.82 -179.47 58.0 2KO0
ASG PRO A 47 47 C Coil -49.42 160.29 51.3 2KO0
ASG THR A 48 48 T Turn -79.29 -169.04 65.3 2KO0
ASG LYS A 49 49 T Turn -58.01 -4.74 55.7 2KO0
ASG TYR A 50 50 T Turn -87.42 -27.59 179.2 2KO0
ASG SER A 51 51 T Turn -74.50 173.09 14.8 2KO0
ASG SER A 52 52 E Strand -108.78 144.50 28.7 2KO0
ASG ILE A 53 53 E Strand -112.70 165.07 0.6 2KO0
ASG CYS A 54 54 E Strand -114.25 157.39 0.0 2KO0
ASG SER A 55 55 G 310Helix -46.04 -59.96 5.6 2KO0
ASG GLU A 56 56 G 310Helix -36.71 -23.64 53.6 2KO0
ASG HIS A 57 57 G 310Helix -81.07 -17.30 2.4 2KO0
ASG PHE A 58 58 C Coil -132.21 166.91 11.5 2KO0
ASG THR A 59 59 C Coil -76.44 144.61 65.5 2KO0
ASG PRO A 60 60 G 310Helix -47.06 -35.40 82.3 2KO0
ASG ASP A 61 61 G 310Helix -58.66 -42.68 95.0 2KO0
ASG SER A 62 62 G 310Helix -93.13 -0.27 1.4 2KO0
ASG PHE A 63 63 T Turn -36.77 -53.47 60.7 2KO0
ASG LYS A 64 64 T Turn -174.42 -140.06 67.7 2KO0
ASG ARG A 65 65 T Turn -62.42 -12.22 174.1 2KO0
ASG GLU A 66 66 T Turn -84.41 6.94 163.8 2KO0
ASG SER A 67 67 T Turn -71.99 -106.27 22.5 2KO0
ASG ASN A 68 68 T Turn -99.04 -74.68 135.3 2KO0
ASG ASN A 69 69 T Turn -96.57 -70.27 131.5 2KO0
ASG LYS A 70 70 T Turn -146.03 1.57 131.9 2KO0
ASG LEU A 71 71 T Turn -149.49 177.22 47.2 2KO0
ASG LEU A 72 72 C Coil -59.23 168.76 12.1 2KO0
ASG LYS A 73 73 T Turn -75.36 121.19 55.0 2KO0
ASG GLU A 74 74 T Turn -52.40 -17.43 88.3 2KO0
ASG ASN A 75 75 T Turn -103.07 13.11 138.9 2KO0
ASG ALA A 76 76 T Turn -119.16 127.59 17.2 2KO0
ASG VAL A 77 77 C Coil -133.75 135.76 46.0 2KO0
ASG PRO A 78 78 T Turn -49.07 104.15 1.0 2KO0
ASG THR A 79 79 T Turn -106.77 -15.02 112.4 2KO0
ASG ILE A 80 80 T Turn -74.68 6.96 91.2 2KO0
ASG PHE A 81 81 T Turn -45.23 -51.76 5.3 2KO0
ASG LEU A 82 82 C Coil -169.81 169.07 68.4 2KO0
ASG GLU A 83 83 C Coil -73.02 -49.28 179.5 2KO0
ASG LEU A 84 84 C Coil -165.77 -75.93 108.0 2KO0
ASG VAL A 85 85 C Coil -148.83 128.72 81.0 2KO0
ASG PRO A 86 86 C Coil -72.51 168.39 68.8 2KO0
ASG ARG A 87 87 C Coil -161.81 360.00 278.0 2KO0