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First International Conference on Humics-based Innovative Technologies

«Natural and Synthetic Polyfunctional Compounds and Nanomaterials in Medicine and Biomedical Technologies»


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November 4-8, 2010, Lomonosov Moscow State University, Moscow, Russia 4-8 2010 ., .. , , http://www.humus.ru/hit-2010/


Programme
November 4 Arrival Day 21:30-24:00 Excursion "Moscow at night" November 5 09:00-10:00 Registration of the HiT-2010 participants (lecture hall 446) Opening of the conference / Welcome addresses (lecture hall 446) 10:00-10:05 Valery V. Lunin, Academician of RAS: Greetings from the Dean of the Department of Chemistry of the Lomonosov MSU 10:05-10:10 Nikolay S. Zefirov, Academician of RAS: Greetings from the Chair of the Organic Chemistry Division and Institute of Physiologically Active Compounds of RAS 10:10-10:15 Oskar I. Koifman, Correspondent Member of RAS, Greetings from the Rector of Ivanovo State Chemical-Technological University 10:15-10:20 Irina V. Perminova, Greetings from the Local Organizing Committee From Multifunctional Compounds to Multifunctional Drugs Chairs: Dr. Norbert Hertkorn and Dr. Kamila Kydralieva 10:20-11:00 Invited Lecture Vladimir V. Bezuglov (Institute of Bioorganic Chemistry of RAS, Moscow) Hybrid polyfunctional molecules: from concept to multifunctional drugs 11:00-11:40 Invited Lecture Philippe Schmitt-Kopplin (Institute of Ecological Chemistry, Helmholtz-Zentrum Muenchen) New insights on molecular processes in environment and health with metabolomics tools 11:40-12:10 Coffee break 12:10-12:50 Invited Lecture Nikolay Melik-Nubarov (Department of Chemistry, Lomonosov MSU) Synthetic macromolecular modulators of drug activity 12:50-13:30 Irina Perminova (Department of Chemistry, Lomonosov MSU) On the path forward to biomedical applications of natural polyfunctional compounds humic substances 13:30-15:00 Lunch Multifunctional Compounds in Therapy and Prophylaxis of Viral Diseases Chairs: Dr. Irina V. Sokolova and Dr. Irina Yu. Vashurina 15:00-15:40 Invited Lecture Edward Karamov (Ivanovsky Institute of Virology of RAMS, Moscow) New biomedical approaches to fight HIV-AIDs 15:40-16:00 Stephan Kremb (Institute of Virology, Helmholtz-Zentrum Muenchen) HIV full-replication technology for broad discovery of multiple classes of HIV inhibitors 16:00-16:20 Georgy Krivtsov (Mechnikov Institute for Vaccine Development, Moscow) Chitosans as prospective adjuvants for vaccine development 16:20-16:30 BashInCom Ltd, Official Sponsor of the HiT-2010 Large-scale production of biologically active humic preparations: Innovative Enterprise "BashInCom Ltd.", Ufa, Russia 16:30-17:00 Coffee Break 17:00-19:00 Poster Session 19:00-22:00 Get-Together Party


November 6 Biological Activity of Humic Substances ­ Mechanisms and Prospects for Biomedical Applications Chairs: Dr. Olga Yakimenko and Dr. Istvan Gebefuegi 9:00-9:40 Invited Lecture Liliya Stepchenko (Department of Veterinary and Animal Physiology, Dniepropetrovsk State Agrarian University, Dniepropetrovsk, Ukraine) The mechanisms of regulatory influence of biologically active substances of humic nature on the organism of animals 9:40-10:20 Invited Lecture Alexandrova Olga (Osnabrueck University ­ Technical University of Ekaterinburg) Application of a quantum statistical model of humic substances to their influence on reduction of red cell aggregation in blood 10:20-10:40 Natalia V. Yudina (Institute of Petroleum Chemistry, Siberian Branch of RAS, Tomsk) Biological activity of humic lipids 10:40-12:50 Coffee Break + Internet Break + Poster Session 12:50-13:30 Invited Lecture Natalia A. Kulikova (Department of Soil Science, Lomonosov MSU, Moscow, Russia) A New Method for Labeling Humic Substances with Tritium: Future Prospects for Biological Studies 13:30-15:00 Lunch 15:00-15:20 Natural and Modified Humic Substances ­ Challenging Candidates for Biomedical Applications Chairs: Dr. Vladimir A. Kholodov and Dr. Elena I. Fedoros Irina V. Sokolova (Tomsk State University, Tomsk, Russia) Detoxifying Abilities of Humic Substances: The Influence of UV Pretreatment 15:20-15:40 Yury V. Zhernov (Samara State Medical University, Samara, Russia) Chemotherapeutic effect of humic substances from low mineralized silt sulphide muds on pathogenic and opportunistic microorganisms 15:40-16:00 Valery N. Babin (Nesmeyanov Institute of Organoelemental Chemistry RAS, "Ultrasun LLC") Development of prophylactic-therapeutic system of biologically active food supplement based on restoration of balance in the system "host-microflora" 16:00-16:20 Alexander I. Popov (Saint Petersburg University, Saint Petersburg) The Removal of Stress at Quails by Humic Substances 16:20-16:40 Tatiana A. Sorkina (Department of Chemistry, Lomonosov MSU, Moscow, Russia) Synthesis and Application of Iron-Humic Compounds for Correction of Iron-Deficiency State of Plants 16:40-16:45 Sponsor of the HiT-2010 "Medbiopharm" LLC (Obninsk, Kaluga District, Russia) Center of Innovation Biotechnology and Pharmaceutics Park of Active Molecules (CIBPh "PAM") 16:45-17:15 Coffee Break 17:15-19:30 Panel Discussion Moderators: Dr. Olga S. Yakimenko and Dr. Istvan L. Gebefuegi Round Table: "Commercial drugs from polyfunctional compounds: myths and reality" Moderators: Dr. Alexander I. Popov and Dr. Sergey E. Pigarev 19:30-21:30 Dinner


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November 7 In search for molecular structure and biological target of polyfunctional compounds Chairs: Dr. Schmitt-Kopplin and Dr. Eugene N. Nikolaev 00-09:40 Invited Lecture Norbert Hertkorn (Institute of Ecological Chemistry, Helmholtz Zentrum Muenchen, Germany) High-precision frequency measurements: indispensable tools at the core of molecularlevel analysis for linking non-targeted and targeted metabolomics of complex systems 40-10:20 Basem Kanawatti (Institute of Ecological Chemistry, Helmholtz Zentrum Muenchen, Germany) Fourier Transform Ion Cyclotron Resonance Mass Spectrometry and Computational Tools in Modern Analytical Chemistry 20-10:40 Anton Grigoriev (Institute of Biochemical Physics of RAS and Institute of Energy Problem of Chemical Physics of RAS) Transhumus: Integrated software solution for interpretation of FT-ICR mass spectra of natural organic matter 40-11:10 Coffee Break Poster Presentation Session Chairs: Natalia V. Yudina and Dr. Nina S. Sedyh 10-11:20 Mourad Harir (Institute of Ecological Chemistry, Helmholtz Zentrum Muenchen, Germany) DCMU complex formation as followed with electrospray Fourier transforms ion cyclotron mass spectrometry 20-11:30 Marianna Lucio (Institute of Ecological Chemistry, Helmholtz Zentrum Muenchen, Germany) Metabolomic study on possible biomarkers of Crohn's disease 30-11:40 Andrey Konstantinov (Department of Chemistry, Lomonosov Moscow State University) Structural Study of Oxidized Lignin Samples using Size-Exclusion Chromatography, NMR Spectroscopy and Fourier Transform Ion Cyclotron Resonance Mass Spectrometry 40-11:50 Gleb Vladimirov (Institute of Biochemical Physics of RAS and Institute of Energy Problem of Chemical Physics of RAS) Combination of high resolution mass-spectrometry (FT-ICR) and nuclear magnetic resonance (NMR) for analysis of mumijo (shilajit) 50-12:00 Michael Kazachkov (Department of Chemistry, Lomonosov Moscow State University) Optimization of electrospray ionization conditions for more informative mass spectra in structural research of HS for applications in medicine 00-12:10 Anastasiya Goldt (Department of Material Science, Lomonosov MSU) Superparamagnetic Iron Oxide Nanoparticles as MRI contrast agents 20-12:30 Alexander Polyakov (Department of Material Science, Lomonosov MSU) Synthesis of Biocompatible Feroxyhyte (d-FeOOH) Magnetic Nanoparticles Using in situ Stabilization with Polyfunctional Humic Macroligands 30-14:00 Lunch


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Poster Presentation Session (continuation) Chairs: Dr. Andrey I. Konstantinov and Dr. Anastasiya E. Goldt 00-14:10 Irina Vashurina (Ivanovo State Chemical-Technology University, Ivanovo, Russia) Prevention of Placental Insufficiency in Rats using Peat Humic Acids 10-14:20 Alexander Volikov (Department of Chemistry, Lomonosov MSU) Synthesis of Adhesive Silanol Derivatives and Their Sorption onto Mineral Support 20-14:30 Evgeniy Garanin (Department of Chemistry, Lomonosov MSU) Synthesis of bioavailable zinc-humic compounds 30-14:40 Alexander Popov (Saint Petersburg State University, Saint Petersburg) Solubilization of Hydrocarbons by Soil Humic Substances 40-14:50 Vladimir Kholodov (Dokuchaev Soil Science Institute, RAAS) Detoxifying Ability of Quinonoid-Enriched Humic Acids with Respect to Copper 50-15:00 Olga Philippova (Department of Soil Science, Lomonosov MSU) Beneficial Effect of Coal Humic Acids and Their Si-enriched Derivative Towards Potatoes and W heat 00-15:10 Nadezhda Sedykh (Department of Veterinary and Animal Physiology, Dniepropetrovsk State Agrarian University, Dniepropetrovsk, Ukraine) Quantitative Criteria of Biological Activity of New Humics-Based Immunomodulators 10-15:20 Polina Zaitseva (Ivanovo State Chemical Technology University, Ivanovo) Viscous properties of the solutions of copolymers used in the synthesis of polymerporphyrins for medical applications 20-15:30 Evgeniy Molchanov (Moscow Aviation Institute (Technical University) Optimization of production methods of polymeric composite materials based on prepreg technology for precision orthopedic technique 30-15:40 Nadezhda Avvakumova (Samara State Medical University) Modern aspects of medical use of drugs humic peloids sequence 40-15:50 Olga Yakimenko (Soil Science Department, Lomonosov MSU) Comparative Sensitivity of Standard Test­Organisms to Commercial Humates of Different Origin 50-16:00 Coffee Break 00-17:00 Closing Remarks. Closure of the conference 00 Departure from the MSU to the Obraztsov Muppet Theatre and conference dinner

November 8, 2010 10:00-11:00 Reception of the German delegation by the Dean of the Department of Chemistry (TBC) 11:00-12:00 Round Table Discussion: Prospects of Russian-German Cooperation in the field of structure elucidation and biomedical applications of humic substances 12:00-14:00 Excursion in the labs of the Lomonosov Moscow State University 14:00-15:30 Lunch Departure