Pfam ID ↓
|
Domain 
|
# of entries 
|
# of domains 
|
# of bound domains 
|
2OG-FeII_Oxy_2
|
2OG-Fe(II) oxygenase superfamily
|
43
|
45
|
44
|
4HBT
|
Thioesterase superfamily
|
1
|
4
|
0
|
5_3_exonuc
|
5'-3' exonuclease, C-terminal SAM fold
|
3
|
3
|
2
|
5_3_exonuc_N
|
5'-3' exonuclease, N-terminal resolvase-like domain
|
4
|
4
|
1
|
7kD_DNA_binding
|
7kD DNA-binding domain
|
19
|
24
|
22
|
AAA
|
ATPase family associated with various cellular activities (AAA)
|
3
|
16
|
16
|
AAA_11
|
AAA domain
|
3
|
4
|
4
|
AAA_12
|
AAA domain
|
3
|
4
|
4
|
AAA_16
|
AAA ATPase domain
|
1
|
1
|
1
|
AAA_19
|
Part of AAA domain
|
1
|
2
|
2
|
AAA_21
|
AAA domain
|
1
|
2
|
0
|
AAA_22
|
AAA domain
|
1
|
2
|
2
|
AAA_23
|
AAA domain
|
1
|
4
|
2
|
AAA_30
|
AAA domain
|
5
|
10
|
8
|
AAA_33
|
AAA domain
|
12
|
26
|
20
|
ABC_tran
|
ABC transporter
|
3
|
6
|
5
|
ABC_tran_2
|
ABC transporter
|
1
|
1
|
1
|
Aconitase
|
Aconitase family (aconitate hydratase)
|
2
|
3
|
3
|
Aconitase_C
|
Aconitase C-terminal domain
|
2
|
3
|
3
|
Activator_LAG-3
|
Transcriptional activator LAG-3
|
1
|
1
|
0
|
Ada_Zn_binding
|
Metal binding domain of Ada
|
2
|
2
|
2
|
Adenine_glyco
|
Methyladenine glycosylase
|
1
|
1
|
1
|
AFT
|
Transcription factor AFT
|
1
|
4
|
4
|
AGT
|
DNA alpha-glucosyltransferase
|
4
|
11
|
11
|
AHSA1
|
Activator of Hsp90 ATPase homolog 1-like protein
|
1
|
1
|
1
|
Alba
|
Alba
|
3
|
7
|
4
|
AlkA_N
|
AlkA N-terminal domain
|
12
|
39
|
0
|
Amidase
|
Amidase
|
3
|
7
|
2
|
Ank
|
Ankyrin repeat
|
4
|
6
|
2
|
Ank_2
|
Ankyrin repeats (3 copies)
|
6
|
16
|
4
|
Ank_4
|
Ankyrin repeats (many copies)
|
1
|
1
|
0
|
Anticodon_1
|
Anticodon-binding domain of tRNA
|
20
|
31
|
31
|
Antitoxin-MazE
|
Antidote-toxin recognition MazE
|
3
|
10
|
10
|
AP2
|
AP2 domain
|
2
|
3
|
3
|
Apolipoprotein
|
Apolipoprotein A1/A4/E domain
|
1
|
2
|
0
|
AP_endonuc_2
|
Xylose isomerase-like TIM barrel
|
4
|
6
|
5
|
Arc
|
Arc-like DNA binding domain
|
4
|
16
|
16
|
Arena_nucleocap
|
Arenavirus nucleocapsid protein
|
7
|
13
|
13
|
Arg_repressor
|
Arginine repressor, DNA binding domain
|
5
|
23
|
23
|
Arg_repressor_C
|
Arginine repressor, C-terminal domain
|
4
|
19
|
0
|
Arg_tRNA_synt_N
|
Arginyl tRNA synthetase N terminal domain
|
4
|
6
|
4
|
ARID
|
ARID/BRIGHT DNA binding domain
|
2
|
2
|
2
|
AsnC_trans_reg
|
AsnC family
|
1
|
1
|
0
|
Asparaginase
|
Asparaginase
|
1
|
2
|
0
|
ATP-synt_ab
|
ATP synthase alpha/beta family, nucleotide-binding domain
|
6
|
36
|
6
|
ATP_bind_3
|
PP-loop family
|
1
|
2
|
2
|
Autoind_bind
|
Autoinducer binding domain
|
2
|
8
|
0
|
Auxin_resp
|
Auxin response factor
|
1
|
2
|
0
|
Avirulence
|
Xanthomonas avirulence protein, Avr/PthA
|
23
|
64
|
64
|
B2
|
RNA binding protein B2
|
2
|
4
|
4
|
B3
|
B3 DNA binding domain
|
1
|
2
|
2
|
B3_4
|
B3/4 domain
|
2
|
4
|
2
|
B5
|
tRNA synthetase B5 domain
|
2
|
4
|
0
|
Bac_DnaA
|
Bacterial dnaA protein
|
1
|
4
|
4
|
Bac_DnaA_C
|
Bacterial dnaA protein helix-turn-helix
|
4
|
9
|
5
|
Bac_DNA_binding
|
Bacterial DNA-binding protein
|
12
|
28
|
28
|
BAF
|
Barrier to autointegration factor
|
1
|
2
|
2
|
BAH
|
BAH domain
|
7
|
20
|
2
|
BamHI
|
Restriction endonuclease BamHI
|
5
|
12
|
11
|
BEN
|
BEN domain
|
2
|
6
|
6
|
Beta-Casp
|
Beta-Casp domain
|
1
|
4
|
4
|
BHD_1
|
Rad4 beta-hairpin domain 1
|
3
|
3
|
3
|
BHD_2
|
Rad4 beta-hairpin domain 2
|
3
|
3
|
3
|
BHD_3
|
Rad4 beta-hairpin domain 3
|
3
|
3
|
3
|
BpuJI_N
|
Restriction endonuclease BpuJI - N terminal
|
1
|
1
|
1
|
BRCA-2_helical
|
BRCA2, helical
|
1
|
1
|
0
|
BRCA-2_OB1
|
BRCA2, oligonucleotide/oligosaccharide-binding, domain 1
|
1
|
1
|
0
|
BRCA-2_OB3
|
BRCA2, oligonucleotide/oligosaccharide-binding, domain 3
|
1
|
1
|
1
|
BRCT
|
BRCA1 C Terminus (BRCT) domain
|
1
|
1
|
1
|
BRF1
|
Brf1-like TBP-binding domain
|
1
|
4
|
0
|
BrkDBD
|
Brinker DNA-binding domain
|
1
|
1
|
1
|
Bromo_coat
|
Bromovirus coat protein
|
1
|
3
|
3
|
Bse634I
|
Cfr10I/Bse634I restriction endonuclease
|
10
|
34
|
32
|
BTD
|
Beta-trefoil DNA-binding domain
|
10
|
12
|
12
|
Btz
|
CASC3/Barentsz eIF4AIII binding
|
5
|
17
|
9
|
Bunya_nucleocap
|
Bunyavirus nucleocapsid (N) protein
|
5
|
24
|
24
|
Bunya_RdRp
|
Bunyavirus RNA dependent RNA polymerase
|
2
|
2
|
2
|
bZIP_1
|
bZIP transcription factor
|
14
|
29
|
29
|
bZIP_2
|
Basic region leucine zipper
|
13
|
30
|
30
|
bZIP_Maf
|
bZIP Maf transcription factor
|
6
|
14
|
12
|
C1-set
|
Immunoglobulin C1-set domain
|
24
|
66
|
3
|
C2-set_2
|
CD80-like C2-set immunoglobulin domain
|
4
|
8
|
5
|
CAF1
|
CAF1 family ribonuclease
|
1
|
2
|
2
|
CarD_CdnL_TRCF
|
CarD-like/TRCF domain
|
2
|
4
|
4
|
Cass2
|
Integron-associated effector binding protein
|
1
|
1
|
1
|
Cas_Cas5d
|
CRISPR-associated protein (Cas_Cas5)
|
5
|
9
|
9
|
Cas_Cas6
|
CRISPR associated protein Cas6
|
4
|
7
|
7
|
Cas_Cmr3
|
CRISPR-associated protein (Cas_Cmr3)
|
1
|
1
|
1
|
Cas_Cmr5
|
CRISPR-associated protein (Cas_Cmr5)
|
1
|
2
|
2
|
Cas_csx3
|
CRISPR-associated protein (Cas_csx3)
|
1
|
2
|
2
|
Cas_Csy4
|
CRISPR-associated protein (Cas_Csy4)
|
6
|
10
|
10
|
Cas_CT1975
|
CT1975-like protein
|
5
|
56
|
55
|
CAT_RBD
|
CAT RNA binding domain
|
1
|
2
|
2
|
Cauli_VI
|
Caulimovirus viroplasmin
|
1
|
6
|
6
|
CBFB_NFYA
|
CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B
|
2
|
2
|
2
|
CBFD_NFYB_HMF
|
Histone-like transcription factor (CBF/NF-Y) and archaeal histone
|
4
|
7
|
7
|
CBF_beta
|
Core binding factor beta subunit
|
9
|
17
|
0
|
CcdA
|
Post-segregation antitoxin CcdA
|
2
|
4
|
4
|
Cdc6_C
|
CDC6, C terminal
|
2
|
3
|
3
|
CENP-B_N
|
CENP-B N-terminal DNA-binding domain
|
1
|
1
|
1
|
CENP-S
|
Kinetochore component CENP-S
|
2
|
30
|
1
|
CENP-X
|
CENP-S associating Centromere protein X
|
2
|
30
|
8
|
CHCH
|
CHCH domain
|
1
|
1
|
0
|
Chordopox_A20R
|
Chordopoxvirus A20R protein
|
1
|
3
|
0
|
Clp1
|
Pre-mRNA cleavage complex II protein Clp1
|
4
|
4
|
4
|
cNMP_binding
|
Cyclic nucleotide-binding domain
|
18
|
36
|
8
|
CoA_binding
|
CoA binding domain
|
3
|
8
|
0
|
Colicin-DNase
|
DNase/tRNase domain of colicin-like bacteriocin
|
6
|
14
|
14
|
Como_LCP
|
Large coat protein
|
2
|
2
|
1
|
Como_SCP
|
Small coat protein
|
2
|
2
|
0
|
Couple_hipA
|
HipA N-terminal domain
|
3
|
6
|
0
|
CPL
|
CPL (NUC119) domain
|
1
|
1
|
1
|
CPSF_A
|
CPSF A subunit region
|
10
|
12
|
0
|
CR6_interact
|
Growth arrest and DNA-damage-inducible proteins-interacting protein 1
|
1
|
1
|
1
|
Cren7
|
Chromatin protein Cren7
|
5
|
7
|
7
|
CRISPR_assoc
|
CRISPR associated protein
|
11
|
23
|
23
|
CRISPR_Cse1
|
CRISPR-associated protein Cse1 (CRISPR_cse1)
|
5
|
9
|
8
|
CRISPR_Cse2
|
CRISPR-associated protein Cse2 (CRISPR_cse2)
|
5
|
18
|
2
|
Cro
|
Cro
|
3
|
9
|
3
|
Crp
|
Bacterial regulatory proteins, crp family
|
15
|
30
|
30
|
CSD
|
'Cold-shock' DNA-binding domain
|
11
|
28
|
25
|
CsrA
|
Global regulator protein family
|
9
|
26
|
26
|
CtsR
|
Firmicute transcriptional repressor of class III stress genes (CtsR)
|
1
|
2
|
2
|
Cucumo_2B
|
Cucumovirus protein 2B
|
2
|
6
|
6
|
Cucumo_coat
|
Cucumovirus coat protein
|
1
|
3
|
0
|
Cullin
|
Cullin family
|
2
|
3
|
0
|
Cullin_Nedd8
|
Cullin protein neddylation domain
|
2
|
3
|
0
|
CUT
|
CUT domain
|
3
|
4
|
4
|
Cyclin_N
|
Cyclin, N-terminal domain
|
1
|
2
|
2
|
Cytotoxic
|
Cytotoxic
|
1
|
1
|
1
|
DALR_1
|
DALR anticodon binding domain
|
4
|
6
|
4
|
DALR_2
|
DALR domain
|
1
|
1
|
1
|
DAP3
|
Mitochondrial ribosomal death-associated protein 3
|
1
|
1
|
1
|
DbpA
|
DbpA RNA binding domain
|
1
|
1
|
1
|
dCMP_cyt_deam_1
|
Cytidine and deoxycytidylate deaminase zinc-binding region
|
1
|
4
|
4
|
DcpS_C
|
Scavenger mRNA decapping enzyme C-term binding
|
4
|
8
|
8
|
DDE_Tnp_1
|
Transposase DDE domain
|
4
|
8
|
8
|
DdrB
|
DdrB-like protein
|
1
|
5
|
3
|
DEAD
|
DEAD/DEAH box helicase
|
42
|
80
|
75
|
DEAD_2
|
DEAD_2
|
1
|
1
|
0
|
Denso_VP4
|
Capsid protein VP4
|
1
|
1
|
1
|
DHHA1
|
DHHA1 domain
|
2
|
4
|
2
|
Dimer_Tnp_Tn5
|
Transposase Tn5 dimerisation domain
|
4
|
8
|
8
|
DKCLD
|
DKCLD (NUC011) domain
|
12
|
12
|
11
|
DM
|
DM DNA binding domain
|
1
|
3
|
3
|
DnaB
|
DnaB-like helicase N terminal domain
|
1
|
12
|
0
|
DnaB_bind
|
DnaB-helicase binding domain of primase
|
1
|
2
|
0
|
DnaB_C
|
DnaB-like helicase C terminal domain
|
1
|
12
|
12
|
DNApol3-delta_C
|
DNA polymerase III, delta subunit, C terminal
|
3
|
6
|
0
|
DNA_alkylation
|
DNA alkylation repair enzyme
|
4
|
4
|
4
|
DNA_binding_1
|
6-O-methylguanine DNA methyltransferase, DNA binding domain
|
11
|
15
|
14
|
DNA_gyraseB
|
DNA gyrase B
|
3
|
5
|
2
|
DNA_gyraseB_C
|
DNA gyrase B subunit, carboxyl terminus
|
21
|
51
|
39
|
DNA_III_psi
|
DNA polymerase III psi subunit
|
1
|
2
|
0
|
DNA_ligase_aden
|
NAD-dependent DNA ligase adenylation domain
|
2
|
2
|
2
|
DNA_ligase_A_C
|
ATP dependent DNA ligase C terminal region
|
2
|
2
|
2
|
DNA_ligase_A_M
|
ATP dependent DNA ligase domain
|
4
|
7
|
7
|
DNA_ligase_A_N
|
DNA ligase N terminus
|
2
|
2
|
2
|
DNA_ligase_OB
|
NAD-dependent DNA ligase OB-fold domain
|
2
|
2
|
2
|
DNA_ligase_OB_2
|
DNA ligase OB-like domain
|
2
|
5
|
5
|
DNA_ligase_ZBD
|
NAD-dependent DNA ligase C4 zinc finger domain
|
2
|
2
|
2
|
DNA_methylase
|
C-5 cytosine-specific DNA methylase
|
32
|
37
|
37
|
DNA_photolyase
|
DNA photolyase
|
11
|
25
|
20
|
DNA_pol3_alpha
|
Bacterial DNA polymerase III alpha subunit
|
5
|
9
|
8
|
DNA_pol3_beta
|
DNA polymerase III beta subunit, N-terminal domain
|
1
|
2
|
2
|
DNA_pol3_beta_2
|
DNA polymerase III beta subunit, central domain
|
1
|
2
|
1
|
DNA_pol3_beta_3
|
DNA polymerase III beta subunit, C-terminal domain
|
1
|
2
|
0
|
DNA_pol3_delta
|
DNA polymerase III, delta subunit
|
3
|
6
|
0
|
DNA_pol3_delta2
|
DNA polymerase III, delta subunit
|
3
|
24
|
24
|
DNA_pol3_delt_C
|
Processivity clamp loader gamma complex DNA pol III C-term
|
3
|
6
|
6
|
DNA_pol3_gamma3
|
DNA polymerase III subunits gamma and tau domain III
|
3
|
18
|
0
|
DNA_pol_A
|
DNA polymerase family A
|
179
|
224
|
222
|
DNA_pol_A_exo1
|
3'-5' exonuclease
|
16
|
17
|
16
|
DNA_pol_B
|
DNA polymerase family B
|
142
|
198
|
193
|
DNA_pol_B_2
|
DNA polymerase type B, organellar and viral
|
6
|
15
|
14
|
DNA_pol_B_exo1
|
DNA polymerase family B, exonuclease domain
|
143
|
208
|
182
|
DNA_pol_B_palm
|
DNA polymerase beta palm
|
305
|
336
|
334
|
DNA_pol_B_thumb
|
DNA polymerase beta thumb
|
308
|
340
|
226
|
DNA_pol_lambd_f
|
Fingers domain of DNA polymerase lambda
|
305
|
336
|
336
|
DNA_PPF
|
DNA polymerase processivity factor
|
3
|
12
|
0
|
DNA_primase_S
|
Eukaryotic and archaeal DNA primase small subunit
|
3
|
8
|
6
|
DNA_processg_A
|
DNA recombination-mediator protein A
|
1
|
2
|
2
|
DNA_RNApol_7kD
|
DNA directed RNA polymerase, 7 kDa subunit
|
87
|
89
|
0
|
DNA_topoisoIV
|
DNA gyrase/topoisomerase IV, subunit A
|
30
|
74
|
69
|
DRP
|
Dam-replacing family
|
2
|
3
|
3
|
DSHCT
|
DSHCT (NUC185) domain
|
1
|
2
|
2
|
dsrm
|
Double-stranded RNA binding motif
|
24
|
42
|
33
|
DSS1_SEM1
|
DSS1/SEM1 family
|
1
|
1
|
0
|
DUF1115
|
Protein of unknown function (DUF1115)
|
1
|
2
|
2
|
DUF1713
|
Mitochondrial domain of unknown function (DUF1713)
|
1
|
1
|
1
|
DUF1743
|
Domain of unknown function (DUF1743)
|
2
|
2
|
2
|
DUF1785
|
Domain of unknown function (DUF1785)
|
20
|
20
|
20
|
DUF217
|
Uncharacterized ACR, COG1753
|
1
|
2
|
2
|
DUF2201
|
VWA-like domain (DUF2201)
|
2
|
4
|
0
|
DUF2209
|
Uncharacterized protein conserved in archaea (DUF2209)
|
2
|
2
|
0
|
DUF2258
|
Uncharacterized protein conserved in archaea (DUF2258)
|
1
|
8
|
8
|
DUF2276
|
Uncharacterized conserved protein (DUF2276)
|
5
|
12
|
12
|
DUF2356
|
Conserved protein (DUF2356)
|
2
|
2
|
0
|
DUF258
|
Protein of unknown function, DUF258
|
2
|
2
|
2
|
DUF3378
|
Domain of unknown function (DUF3378)
|
3
|
3
|
3
|
DUF3578
|
Domain of unknown function (DUF3578)
|
3
|
6
|
6
|
DUF3692
|
CRISPR-associated protein
|
1
|
1
|
0
|
DUF4102
|
Domain of unknown function (DUF4102)
|
1
|
2
|
2
|
DUF4152
|
Protein of unknown function (DUF4152)
|
4
|
12
|
12
|
DUF445
|
Protein of unknown function (DUF445)
|
1
|
1
|
1
|
DUF727
|
Protein of unknown function (DUF727)
|
1
|
1
|
1
|
Dus
|
Dihydrouridine synthase (Dus)
|
4
|
8
|
8
|
DZR
|
Double zinc ribbon
|
89
|
89
|
69
|
E2F_TDP
|
E2F/DP family winged-helix DNA-binding domain
|
1
|
2
|
2
|
EAL
|
EAL domain
|
2
|
4
|
4
|
EBV-NA1
|
Epstein Barr virus nuclear antigen-1, DNA-binding domain
|
1
|
2
|
2
|
EcoRI
|
Restriction endonuclease EcoRI
|
6
|
12
|
12
|
EcoRII-C
|
EcoRII C terminal
|
3
|
10
|
10
|
EcoRII-N
|
Restriction endonuclease EcoRII, N-terminal
|
1
|
1
|
1
|
ECR1_N
|
Exosome complex exonuclease RRP4 N-terminal region
|
6
|
10
|
0
|
EFG_C
|
Elongation factor G C-terminus
|
38
|
38
|
2
|
EFG_II
|
Elongation Factor G, domain II
|
40
|
40
|
12
|
EFG_IV
|
Elongation factor G, domain IV
|
36
|
36
|
29
|
EFP
|
Elongation factor P (EF-P) OB domain
|
2
|
2
|
2
|
EFP_N
|
Elongation factor P (EF-P) KOW-like domain
|
2
|
2
|
2
|
EF_TS
|
Elongation factor TS
|
9
|
9
|
0
|
eIF-1a
|
Translation initiation factor 1A / IF-1
|
11
|
11
|
10
|
eIF-3c_N
|
Eukaryotic translation initiation factor 3 subunit 8 N-terminus
|
1
|
1
|
1
|
eIF-6
|
eIF-6 family
|
6
|
6
|
1
|
eIF2A
|
Eukaryotic translation initiation factor eIF2A
|
1
|
1
|
1
|
eIF2_C
|
Initiation factor eIF2 gamma, C terminal
|
3
|
3
|
1
|
EIF_2_alpha
|
Eukaryotic translation initiation factor 2 alpha subunit
|
4
|
4
|
2
|
Elong-fact-P_C
|
Elongation factor P, C-terminal
|
2
|
2
|
2
|
EMG1
|
EMG1/NEP1 methyltransferase
|
2
|
4
|
4
|
EndIII_4Fe-2S
|
Iron-sulfur binding domain of endonuclease III
|
10
|
11
|
4
|
Endonuc-BglII
|
Restriction endonuclease BglII
|
4
|
8
|
8
|
Endonuc-BsobI
|
Restriction endonuclease BsobI
|
1
|
2
|
2
|
Endonuc-dimeris
|
T4 recombination endonuclease VII, dimerisation
|
2
|
4
|
4
|
Endonuc-EcoRV
|
Restriction endonuclease EcoRV
|
28
|
58
|
58
|
Endonuc-FokI_C
|
Restriction endonuclease FokI, C terminal
|
1
|
1
|
1
|
Endonuc-HincII
|
Restriction endonuclease HincII
|
18
|
50
|
49
|
Endonuc-MspI
|
Restriction endonuclease MspI
|
2
|
4
|
4
|
Endonuc-PvuII
|
Restriction endonuclease PvuII
|
5
|
10
|
10
|
Endonuclease_1
|
Endonuclease I
|
2
|
6
|
6
|
Endonuclease_5
|
Endonuclease V
|
3
|
6
|
2
|
Endonuclease_7
|
Recombination endonuclease VII
|
4
|
8
|
8
|
Endonuc_BglI
|
Restriction endonuclease BglI
|
1
|
2
|
2
|
ERCC4
|
ERCC4 domain
|
6
|
19
|
9
|
eRF1_1
|
eRF1 domain 1
|
5
|
5
|
4
|
eRF1_2
|
eRF1 domain 2
|
5
|
5
|
2
|
eRF1_3
|
eRF1 domain 3
|
5
|
5
|
2
|
Ets
|
Ets-domain
|
36
|
62
|
62
|
Exc
|
Excisionase-like protein
|
3
|
7
|
6
|
Exonuc_V_gamma
|
Exodeoxyribonuclease V, gamma subunit
|
2
|
4
|
2
|
Exonuc_X-T_C
|
Exonuclease C-terminal
|
6
|
18
|
18
|
EXOSC1
|
Exosome component EXOSC1/CSL4
|
4
|
4
|
0
|
Exo_endo_phos
|
Endonuclease/Exonuclease/phosphatase family
|
29
|
65
|
62
|
FadR_C
|
FadR C-terminal domain
|
3
|
8
|
0
|
FAD_binding_7
|
FAD binding domain of DNA photolyase
|
11
|
25
|
20
|
Fapy_DNA_glyco
|
Formamidopyrimidine-DNA glycosylase N-terminal domain
|
69
|
80
|
80
|
FDX-ACB
|
Ferredoxin-fold anticodon binding domain
|
3
|
5
|
5
|
FemAB
|
FemAB family
|
1
|
2
|
1
|
FeoA
|
FeoA domain
|
2
|
9
|
0
|
Fer4
|
4Fe-4S binding domain
|
1
|
1
|
0
|
Fe_dep_repress
|
Iron dependent repressor, N-terminal DNA binding domain
|
6
|
28
|
28
|
Fe_dep_repr_C
|
Iron dependent repressor, metal binding and dimerisation domain
|
6
|
28
|
0
|
Fibrillarin
|
Fibrillarin
|
5
|
14
|
3
|
Filo_VP35
|
Filoviridae VP35
|
5
|
17
|
15
|
FKBP_C
|
FKBP-type peptidyl-prolyl cis-trans isomerase
|
1
|
2
|
0
|
Flavi_DEAD
|
Flavivirus DEAD domain
|
13
|
29
|
26
|
Flexi_CP
|
Viral coat protein
|
1
|
25
|
25
|
FLO_LFY
|
Floricaula / Leafy protein
|
1
|
2
|
2
|
Flp_C
|
Recombinase Flp protein
|
3
|
12
|
12
|
Flp_N
|
Recombinase Flp protein N-terminus
|
3
|
12
|
12
|
Flu_NP
|
Influenza virus nucleoprotein
|
1
|
72
|
0
|
Flu_NS1
|
Influenza non-structural protein (NS1)
|
1
|
2
|
2
|
Flu_PA
|
Influenza RNA-dependent RNA polymerase subunit PA
|
4
|
7
|
5
|
Flu_PB1
|
Influenza RNA-dependent RNA polymerase subunit PB1
|
4
|
5
|
3
|
Flu_PB2
|
Influenza RNA-dependent RNA polymerase subunit PB2
|
3
|
3
|
3
|
FokI_C
|
Restriction endonuclease FokI, catalytic domain
|
1
|
1
|
1
|
FokI_N
|
Restriction endonuclease FokI, recognition domain
|
1
|
1
|
1
|
Fork_head
|
Fork head domain
|
14
|
27
|
27
|
Formyl_trans_C
|
Formyl transferase, C-terminal domain
|
1
|
2
|
2
|
Formyl_trans_N
|
Formyl transferase
|
1
|
2
|
2
|
FtsJ
|
FtsJ-like methyltransferase
|
2
|
6
|
4
|
Ftsk_gamma
|
Ftsk gamma domain
|
1
|
6
|
6
|
FUR
|
Ferric uptake regulator family
|
4
|
12
|
12
|
G-gamma
|
GGL domain
|
1
|
1
|
0
|
GAD
|
GAD domain
|
5
|
11
|
2
|
GAGA
|
GAGA factor
|
2
|
2
|
2
|
Gal4_dimer
|
Gal4-like dimerisation domain
|
2
|
4
|
4
|
Gar1
|
Gar1/Naf1 RNA binding region
|
4
|
4
|
0
|
GATA
|
GATA zinc finger
|
16
|
27
|
25
|
GatB_N
|
GatB/GatE catalytic domain
|
4
|
9
|
8
|
GatB_Yqey
|
GatB domain
|
3
|
7
|
5
|
GCM
|
GCM motif protein
|
1
|
1
|
1
|
GerE
|
Bacterial regulatory proteins, luxR family
|
9
|
28
|
28
|
Glu-tRNAGln
|
Glu-tRNAGln amidotransferase C subunit
|
3
|
7
|
0
|
GntR
|
Bacterial regulatory proteins, gntR family
|
8
|
20
|
20
|
gp45-slide_C
|
gp45 sliding clamp, C terminal
|
3
|
12
|
2
|
GreA_GreB
|
Transcription elongation factor, GreA/GreB, C-term
|
2
|
6
|
0
|
GreA_GreB_N
|
Transcription elongation factor, N-terminal
|
2
|
6
|
0
|
Gti1_Pac2
|
Gti1/Pac2 family
|
3
|
8
|
8
|
GTP1_OBG
|
GTP1/OBG
|
1
|
1
|
1
|
GTP_EFTU
|
Elongation factor Tu GTP binding domain
|
89
|
108
|
33
|
GTP_EFTU_D2
|
Elongation factor Tu domain 2
|
89
|
94
|
64
|
GTP_EFTU_D3
|
Elongation factor Tu C-terminal domain
|
40
|
44
|
29
|
GTP_EFTU_D4
|
Elongation factor Tu domain 4
|
3
|
3
|
3
|
GyrI-like
|
GyrI-like small molecule binding domain
|
8
|
18
|
0
|
H2TH
|
Formamidopyrimidine-DNA glycosylase H2TH domain
|
69
|
80
|
79
|
HAND
|
HAND
|
1
|
1
|
0
|
HATPase_c
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
|
3
|
5
|
0
|
HD
|
HD domain
|
4
|
16
|
11
|
HD_assoc
|
Phosphohydrolase-associated domain
|
1
|
6
|
0
|
Helicase_C
|
Helicase conserved C-terminal domain
|
55
|
110
|
100
|
Helicase_C_2
|
Helicase C-terminal domain
|
1
|
1
|
1
|
Herpes_alk_exo
|
Herpesvirus alkaline exonuclease
|
1
|
1
|
1
|
HGTP_anticodon
|
Anticodon binding domain
|
6
|
19
|
13
|
HHH
|
Helix-hairpin-helix motif
|
13
|
14
|
14
|
HhH-GPD
|
HhH-GPD superfamily base excision DNA repair protein
|
73
|
111
|
111
|
HHH_2
|
Helix-hairpin-helix motif
|
3
|
4
|
3
|
HHH_4
|
Helix-hairpin-helix containing domain
|
2
|
3
|
3
|
HHH_5
|
Helix-hairpin-helix domain
|
10
|
19
|
12
|
HHH_6
|
Helix-hairpin-helix motif
|
5
|
9
|
5
|
HHH_8
|
Helix-hairpin-helix domain
|
304
|
336
|
240
|
HIN
|
HIN-200/IF120x domain
|
8
|
19
|
18
|
HipA_C
|
HipA-like C-terminal domain
|
3
|
6
|
0
|
HipA_N
|
HipA-like N-terminal domain
|
3
|
6
|
0
|
HIRAN
|
HIRAN domain
|
1
|
4
|
4
|
Histone
|
Core histone H2A/H2B/H3/H4
|
99
|
856
|
841
|
Histone_HNS
|
H-NS histone family
|
1
|
1
|
1
|
HIT
|
HIT domain
|
2
|
8
|
8
|
Hjc
|
Archaeal holliday junction resolvase (hjc)
|
1
|
2
|
1
|
HLH
|
Helix-loop-helix DNA-binding domain
|
16
|
44
|
44
|
HMG_box
|
HMG (high mobility group) box
|
19
|
34
|
33
|
HMG_box_2
|
HMG-box domain
|
6
|
14
|
14
|
HNF-1_N
|
Hepatocyte nuclear factor 1 (HNF-1), N terminus
|
2
|
4
|
4
|
HNH_3
|
HNH endonuclease
|
1
|
1
|
1
|
HNH_4
|
HNH endonuclease
|
8
|
9
|
0
|
Homeobox
|
Homeobox domain
|
51
|
102
|
102
|
Hom_end
|
Homing endonuclease
|
2
|
4
|
4
|
Hom_end_hint
|
Hom_end-associated Hint
|
2
|
2
|
2
|
Hormone_recep
|
Ligand-binding domain of nuclear hormone receptor
|
6
|
16
|
0
|
HPD
|
Homeo-prospero domain
|
1
|
1
|
1
|
HRDC
|
HRDC domain
|
5
|
6
|
2
|
HsdM_N
|
HsdM N-terminal domain
|
1
|
2
|
0
|
HSF_DNA-bind
|
HSF-type DNA-binding
|
3
|
10
|
6
|
HTH_1
|
Bacterial regulatory helix-turn-helix protein, lysR family
|
2
|
12
|
12
|
HTH_12
|
Ribonuclease R winged-helix domain
|
2
|
2
|
2
|
HTH_18
|
Helix-turn-helix domain
|
4
|
7
|
7
|
HTH_19
|
Helix-turn-helix domain
|
7
|
16
|
16
|
HTH_24
|
Winged helix-turn-helix DNA-binding
|
4
|
8
|
8
|
HTH_27
|
Winged helix DNA-binding domain
|
3
|
26
|
25
|
HTH_3
|
Helix-turn-helix
|
30
|
89
|
84
|
HTH_31
|
Helix-turn-helix domain
|
2
|
4
|
4
|
HTH_5
|
Bacterial regulatory protein, arsR family
|
2
|
8
|
8
|
HTH_7
|
Helix-turn-helix domain of resolvase
|
14
|
27
|
27
|
HTH_8
|
Bacterial regulatory protein, Fis family
|
16
|
32
|
32
|
HTH_AraC
|
Bacterial regulatory helix-turn-helix proteins, AraC family
|
1
|
1
|
1
|
HTH_AsnC-type
|
AsnC-type helix-turn-helix domain
|
1
|
1
|
1
|
HTH_Crp_2
|
Crp-like helix-turn-helix domain
|
3
|
6
|
6
|
HTH_IclR
|
IclR helix-turn-helix domain
|
1
|
4
|
4
|
HTH_Tnp_Mu_1
|
Mu DNA-binding domain
|
1
|
1
|
1
|
HTH_Tnp_Tc3_1
|
Tc3 transposase
|
2
|
2
|
2
|
HTH_Tnp_Tc5
|
Tc5 transposase DNA-binding domain
|
1
|
1
|
1
|
HutP
|
HutP
|
4
|
24
|
24
|
HxlR
|
HxlR-like helix-turn-helix
|
1
|
2
|
2
|
IBD
|
Transcription-initiator DNA-binding domain IBD
|
2
|
7
|
5
|
IBR
|
IBR domain
|
42
|
44
|
25
|
IclR
|
Bacterial transcriptional regulator
|
1
|
4
|
0
|
IF-2
|
Translation-initiation factor 2
|
5
|
5
|
0
|
IF3_C
|
Translation initiation factor IF-3, C-terminal domain
|
1
|
1
|
0
|
IgG_binding_B
|
B domain
|
1
|
1
|
0
|
Ig_2
|
Immunoglobulin domain
|
4
|
8
|
8
|
IL6
|
Interleukin-6/G-CSF/MGF family
|
2
|
3
|
3
|
Img2
|
Mitochondrial large subunit ribosomal protein (Img2)
|
3
|
3
|
2
|
IMS
|
impB/mucB/samB family
|
239
|
317
|
314
|
IMS_C
|
impB/mucB/samB family C-terminal domain
|
231
|
309
|
309
|
IMS_HHH
|
IMS family HHH motif
|
181
|
259
|
253
|
IncA
|
IncA protein
|
3
|
5
|
5
|
Integrase_DNA
|
DNA binding domain of tn916 integrase
|
2
|
2
|
2
|
IPPT
|
IPP transferase
|
7
|
26
|
26
|
IRF
|
Interferon regulatory factor transcription factor
|
7
|
22
|
21
|
KH_1
|
KH domain
|
20
|
48
|
41
|
KH_2
|
KH domain
|
451
|
452
|
60
|
KH_5
|
NusA-like KH domain
|
2
|
3
|
3
|
KH_dom-like
|
KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
|
1
|
1
|
1
|
KilA-N
|
KilA-N domain
|
1
|
2
|
2
|
KorB
|
KorB domain
|
1
|
4
|
4
|
KOW
|
KOW motif
|
479
|
517
|
436
|
KTI12
|
Chromatin associated protein KTI12
|
3
|
6
|
6
|
Ku
|
Ku70/Ku80 beta-barrel domain
|
1
|
2
|
2
|
Ku_C
|
Ku70/Ku80 C-terminal arm
|
1
|
2
|
1
|
Ku_N
|
Ku70/Ku80 N-terminal alpha/beta domain
|
1
|
2
|
1
|
L31
|
Mitochondrial ribosomal protein L31
|
1
|
1
|
0
|
L51_S25_CI-B8
|
Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
|
3
|
3
|
2
|
La
|
La domain
|
7
|
13
|
12
|
LacI
|
Bacterial regulatory proteins, lacI family
|
40
|
85
|
81
|
Lactamase_B
|
Metallo-beta-lactamase superfamily
|
3
|
8
|
8
|
Lactamase_B_2
|
Beta-lactamase superfamily domain
|
2
|
3
|
3
|
LAG1-DNAbind
|
LAG1, DNA binding
|
10
|
12
|
12
|
LAGLIDADG_1
|
LAGLIDADG endonuclease
|
49
|
122
|
120
|
LAGLIDADG_2
|
LAGLIDADG DNA endonuclease family
|
5
|
6
|
6
|
LAGLIDADG_3
|
LAGLIDADG-like domain
|
16
|
94
|
94
|
Ldh_1_C
|
lactate/malate dehydrogenase, alpha/beta C-terminal domain
|
1
|
4
|
2
|
Ldh_1_N
|
lactate/malate dehydrogenase, NAD binding domain
|
1
|
4
|
4
|
Lectin_legB
|
Legume lectin domain
|
1
|
4
|
4
|
LepA_C
|
GTP-binding protein LepA C-terminus
|
2
|
2
|
2
|
Leucyl-specific
|
Leucine-tRNA synthetase-specific domain
|
3
|
6
|
0
|
Levi_coat
|
Levivirus coat protein
|
30
|
89
|
88
|
LexA_DNA_bind
|
LexA DNA binding domain
|
3
|
6
|
4
|
LIM
|
LIM domain
|
1
|
2
|
0
|
Linker_histone
|
linker histone H1 and H5 family
|
1
|
1
|
1
|
LRR_4
|
Leucine Rich repeats (2 copies)
|
3
|
5
|
5
|
LRR_8
|
Leucine rich repeat
|
6
|
59
|
28
|
LRR_9
|
Leucine-rich repeat
|
1
|
2
|
2
|
LSM
|
LSM domain
|
20
|
296
|
215
|
Lys
|
C-type lysozyme/alpha-lactalbumin family
|
2
|
7
|
7
|
LytTR
|
LytTr DNA-binding domain
|
1
|
1
|
1
|
L_protein_N
|
L protein N-terminus
|
2
|
2
|
0
|
Mab-21
|
Mab-21 protein
|
10
|
16
|
16
|
Macro
|
Macro domain
|
2
|
8
|
4
|
Mago_nashi
|
Mago nashi protein
|
5
|
9
|
0
|
MamL-1
|
MamL-1 domain
|
3
|
4
|
0
|
MarR
|
MarR family
|
4
|
12
|
12
|
MarR_2
|
MarR family
|
6
|
27
|
21
|
MBD
|
Methyl-CpG binding domain
|
9
|
10
|
10
|
MCM_N
|
MCM N-terminal domain
|
1
|
12
|
0
|
Med11
|
Mediator complex protein
|
1
|
1
|
0
|
Med17
|
Subunit 17 of Mediator complex
|
1
|
1
|
0
|
Med18
|
Med18 protein
|
1
|
1
|
0
|
Med20
|
TATA-binding related factor (TRF) of subunit 20 of Mediator complex
|
1
|
1
|
0
|
Med22
|
Surfeit locus protein 5 subunit 22 of Mediator complex
|
1
|
1
|
0
|
Med6
|
MED6 mediator sub complex component
|
1
|
1
|
0
|
Med8
|
Mediator of RNA polymerase II transcription complex subunit 8
|
1
|
1
|
0
|
MEF2_binding
|
MEF2 binding
|
1
|
1
|
0
|
MerR_1
|
MerR HTH family regulatory protein
|
11
|
21
|
20
|
Metallophos
|
Calcineurin-like phosphoesterase
|
6
|
26
|
18
|
Methylase_S
|
Type I restriction modification DNA specificity domain
|
1
|
2
|
2
|
MethyltransfD12
|
D12 class N6 adenine-specific DNA methyltransferase
|
15
|
26
|
24
|
Methyltransf_1N
|
6-O-methylguanine DNA methyltransferase, ribonuclease-like domain
|
3
|
6
|
0
|
Methyltransf_23
|
Methyltransferase domain
|
1
|
2
|
2
|
Methyltransf_26
|
Methyltransferase domain
|
9
|
16
|
16
|
Methyltransf_4
|
Putative methyltransferase
|
1
|
1
|
1
|
MetJ
|
Met Apo-repressor, MetJ
|
6
|
24
|
24
|
Met_10
|
Met-10+ like-protein
|
2
|
3
|
3
|
MH1
|
MH1 domain
|
7
|
20
|
20
|
Mhr1
|
Transcriptional regulation of mitochondrial recombination
|
1
|
1
|
0
|
Microvir_J
|
Microvirus J protein
|
2
|
2
|
2
|
Mitoc_L55
|
Mitochondrial ribosomal protein L55
|
1
|
1
|
0
|
MMR_HSR1
|
50S ribosome-binding GTPase
|
7
|
8
|
4
|
MMS1_N
|
Mono-functional DNA-alkylating methyl methanesulfonate N-term
|
10
|
12
|
0
|
MobA_MobL
|
MobA/MobL family
|
1
|
1
|
1
|
MobB
|
Molybdopterin guanine dinucleotide synthesis protein B
|
4
|
4
|
4
|
Mob_Pre
|
Plasmid recombination enzyme
|
5
|
6
|
6
|
MogR_DNAbind
|
DNA binding domain of the motility gene repressor (MogR)
|
1
|
2
|
2
|
MRP
|
Mitochondrial RNA binding protein MRP
|
1
|
2
|
2
|
MRP-63
|
Mitochondrial ribosome protein 63
|
1
|
1
|
1
|
MRP-L20
|
Mitochondrial ribosomal protein subunit L20
|
1
|
1
|
0
|
MRP-L27
|
Mitochondrial ribosomal protein L27
|
2
|
2
|
1
|
MRP-L28
|
Mitochondrial ribosomal protein L28
|
2
|
2
|
1
|
MRP-L46
|
39S mitochondrial ribosomal protein L46
|
1
|
1
|
0
|
MRP-L47
|
Mitochondrial 39-S ribosomal protein L47 (MRP-L47)
|
4
|
4
|
1
|
MRP-L51
|
Mitochondrial ribosomal subunit
|
1
|
1
|
1
|
MRP-S22
|
Mitochondrial 28S ribosomal protein S22
|
1
|
1
|
0
|
MRP-S23
|
Mitochondrial ribosomal protein S23
|
1
|
1
|
1
|
MRP-S24
|
Mitochondrial ribosome subunit S24
|
2
|
2
|
2
|
MRP-S26
|
Mitochondrial ribosome subunit S26
|
1
|
1
|
1
|
MRP-S28
|
Mitochondrial ribosomal subunit protein
|
1
|
1
|
1
|
MRP-S31
|
Mitochondrial 28S ribosomal protein S31
|
1
|
1
|
0
|
MRP-S32
|
Mitochondrial 28S ribosomal protein S32
|
1
|
1
|
1
|
MRP-S33
|
Mitochondrial ribosomal subunit S27
|
1
|
1
|
1
|
MRP-S35
|
Mitochondrial ribosomal protein MRP-S35
|
1
|
1
|
1
|
MRP_L53
|
39S ribosomal protein L53/MRP-L53
|
1
|
1
|
1
|
Mrr_cat
|
Restriction endonuclease
|
1
|
4
|
0
|
Mrr_cat_2
|
Restriction endonuclease
|
1
|
2
|
0
|
mTERF
|
mTERF
|
4
|
4
|
4
|
MutH
|
DNA mismatch repair enzyme MutH
|
2
|
3
|
3
|
MutS_I
|
MutS domain I
|
25
|
51
|
39
|
MutS_II
|
MutS domain II
|
25
|
50
|
0
|
MutS_III
|
MutS domain III
|
25
|
50
|
49
|
MutS_IV
|
MutS family domain IV
|
25
|
50
|
48
|
MutS_V
|
MutS domain V
|
25
|
50
|
0
|
MvaI_BcnI
|
MvaI/BcnI restriction endonuclease family
|
4
|
10
|
10
|
Myb_DNA-binding
|
Myb-like DNA-binding domain
|
10
|
15
|
15
|
Myb_DNA-bind_6
|
Myb-like DNA-binding domain
|
10
|
15
|
15
|
Myc-LZ
|
Myc leucine zipper domain
|
1
|
2
|
0
|
N36
|
36-mer N-terminal peptide of the N protein (N36)
|
1
|
1
|
1
|
N6_Mtase
|
N-6 DNA Methylase
|
2
|
4
|
4
|
N6_N4_Mtase
|
DNA methylase
|
1
|
2
|
2
|
NaeI
|
Restriction endonuclease NaeI
|
1
|
2
|
2
|
NAM
|
No apical meristem (NAM) protein
|
2
|
8
|
8
|
NDT80_PhoG
|
NDT80 / PhoG like DNA-binding family
|
11
|
11
|
11
|
NGF
|
Nerve growth factor family
|
1
|
2
|
2
|
NgoMIV_restric
|
NgoMIV restriction enzyme
|
1
|
4
|
4
|
NikR_C
|
NikR C terminal nickel binding domain
|
1
|
8
|
4
|
Nop
|
Putative snoRNA binding domain
|
9
|
26
|
26
|
Nop10p
|
Nucleolar RNA-binding protein, Nop10p family
|
12
|
12
|
9
|
NOSIC
|
NOSIC (NUC001) domain
|
9
|
26
|
2
|
NotI
|
Restriction endonuclease NotI
|
1
|
2
|
2
|
NTP_transf_2
|
Nucleotidyltransferase domain
|
41
|
76
|
69
|
NUDIX
|
NUDIX domain
|
6
|
10
|
3
|
NUDIX_2
|
Nucleotide hydrolase
|
4
|
12
|
9
|
NUDIX_4
|
NUDIX domain
|
10
|
11
|
11
|
NUMOD3
|
NUMOD3 motif (2 copies)
|
2
|
2
|
2
|
NUMOD4
|
NUMOD4 motif
|
1
|
1
|
1
|
NusB
|
NusB family
|
3
|
12
|
7
|
OAS1_C
|
2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus
|
5
|
5
|
5
|
OB_RNB
|
Ribonuclease B OB domain
|
1
|
1
|
0
|
OGG_N
|
8-oxoguanine DNA glycosylase, N-terminal domain
|
30
|
32
|
1
|
Omega_Repress
|
Omega Transcriptional Repressor
|
3
|
12
|
12
|
P22_Cro
|
DNA-binding transcriptional regulator Cro
|
1
|
2
|
2
|
P53
|
P53 DNA-binding domain
|
24
|
116
|
116
|
P53_tetramer
|
P53 tetramerisation motif
|
4
|
16
|
0
|
PADR1
|
PADR1 (NUC008) domain
|
4
|
8
|
0
|
PAP_assoc
|
Cid1 family poly A polymerase
|
1
|
2
|
2
|
PAP_central
|
Poly(A) polymerase central domain
|
1
|
1
|
1
|
PAP_RNA-bind
|
Poly(A) polymerase predicted RNA binding domain
|
1
|
1
|
1
|
Paramyxo_ncap
|
Paramyxovirus nucleocapsid protein
|
2
|
14
|
14
|
ParB
|
ParB family
|
5
|
7
|
6
|
ParBc
|
ParB-like nuclease domain
|
1
|
4
|
0
|
PARP
|
Poly(ADP-ribose) polymerase catalytic domain
|
4
|
8
|
0
|
PARP_reg
|
Poly(ADP-ribose) polymerase, regulatory domain
|
4
|
8
|
0
|
PARP_regulatory
|
Poly A polymerase regulatory subunit
|
4
|
6
|
3
|
Parvo_coat
|
Parvovirus coat protein VP2
|
8
|
8
|
8
|
PAS
|
PAS fold
|
2
|
4
|
2
|
PAS_11
|
PAS domain
|
2
|
4
|
0
|
PAX
|
'Paired box' domain
|
4
|
6
|
6
|
PAZ
|
PAZ domain
|
30
|
38
|
37
|
PBP
|
Phosphatidylethanolamine-binding protein
|
3
|
3
|
0
|
PC4
|
Transcriptional Coactivator p15 (PC4)
|
4
|
12
|
12
|
PCI
|
PCI domain
|
1
|
2
|
0
|
PCNA_C
|
Proliferating cell nuclear antigen, C-terminal domain
|
1
|
3
|
1
|
PCNA_N
|
Proliferating cell nuclear antigen, N-terminal domain
|
1
|
3
|
1
|
PCRF
|
PCRF domain
|
15
|
15
|
12
|
PD-C2-AF1
|
POU domain, class 2, associating factor 1
|
1
|
2
|
2
|
PDCD9
|
Mitochondrial 28S ribosomal protein S30 (PDCD9)
|
1
|
2
|
2
|
PDDEXK_1
|
PD-(D/E)XK nuclease superfamily
|
7
|
14
|
6
|
PDDEXK_5
|
PD-(D/E)XK endonuclease
|
1
|
4
|
2
|
PemK
|
PemK-like protein
|
2
|
4
|
4
|
Penicillinase_R
|
Penicillinase repressor
|
4
|
9
|
9
|
Peptidase_A21
|
Peptidase family A21
|
1
|
8
|
1
|
Peptidase_A6
|
Peptidase A6 family
|
7
|
31
|
9
|
Peptidase_S24
|
Peptidase S24-like
|
4
|
8
|
0
|
Peptidase_S29
|
Hepatitis C virus NS3 protease
|
2
|
4
|
0
|
Peptidase_S48
|
Peptidase family S48
|
5
|
12
|
12
|
Pept_tRNA_hydro
|
Peptidyl-tRNA hydrolase
|
1
|
2
|
2
|
Peripla_BP_3
|
Periplasmic binding protein-like domain
|
31
|
72
|
0
|
PH
|
PH domain
|
2
|
2
|
0
|
Phage_CII
|
Bacteriophage CII protein
|
1
|
4
|
4
|
Phage_coat
|
Phage PP7 coat protein
|
1
|
12
|
12
|
Phage_endo_I
|
Phage endonuclease I
|
1
|
2
|
2
|
Phage_F
|
Capsid protein (F protein)
|
2
|
4
|
4
|
Phage_G
|
Major spike protein (G protein)
|
2
|
2
|
0
|
Phage_integrase
|
Phage integrase family
|
26
|
98
|
98
|
Phage_integ_N
|
Bacteriophage lambda integrase, N-terminal domain
|
3
|
9
|
9
|
Phage_int_SAM_1
|
Phage integrase, N-terminal SAM-like domain
|
2
|
6
|
6
|
Phage_int_SAM_4
|
Phage integrase, N-terminal SAM-like domain
|
23
|
88
|
88
|
Phe_tRNA-synt_N
|
Aminoacyl tRNA synthetase class II, N-terminal domain
|
2
|
4
|
4
|
Phi-29_GP16_7
|
Bacteriophage phi-29 early protein GP16.7
|
1
|
6
|
2
|
Phi-29_GP4
|
Phi-29-like late genes activator (early protein GP4)
|
1
|
2
|
2
|
PHP
|
PHP domain
|
7
|
12
|
0
|
PIN
|
PIN domain
|
3
|
12
|
0
|
PIN_4
|
PIN domain
|
3
|
3
|
0
|
Piwi
|
Piwi domain
|
40
|
55
|
51
|
Pkinase
|
Protein kinase domain
|
3
|
4
|
2
|
Plasmid_stabil
|
Plasmid stabilisation system protein
|
2
|
2
|
2
|
Plasmid_Txe
|
Plasmid encoded toxin Txe
|
2
|
2
|
2
|
Plug_translocon
|
Plug domain of Sec61p
|
7
|
7
|
0
|
PMC2NT
|
PMC2NT (NUC016) domain
|
1
|
2
|
0
|
Pneumovirus_M2
|
Pneumovirus matrix protein 2 (M2)
|
1
|
4
|
0
|
Pneumo_ncap
|
Pneumovirus nucleocapsid protein
|
5
|
93
|
93
|
PNK3P
|
Polynucleotide kinase 3 phosphatase
|
5
|
6
|
6
|
PolC_DP2
|
DNA polymerase II large subunit DP2
|
12
|
12
|
9
|
PolyA_pol
|
Poly A polymerase head domain
|
12
|
20
|
19
|
PolyA_pol_RNAbd
|
Probable RNA and SrmB- binding site of polymerase A
|
12
|
20
|
14
|
Polyoma_lg_T_C
|
Polyomavirus large T antigen C-terminus
|
1
|
4
|
4
|
POT1
|
Telomeric single stranded DNA binding POT1/CDC13
|
22
|
64
|
48
|
POTRA_1
|
POTRA domain, FtsQ-type
|
1
|
1
|
0
|
Pou
|
Pou domain - N-terminal to homeobox domain
|
10
|
21
|
21
|
Pox_polyA_pol
|
Poxvirus poly(A) polymerase nucleotidyltransferase domain
|
3
|
5
|
5
|
Pox_polyA_pol_C
|
Poxvirus poly(A) polymerase C-terminal domain
|
3
|
5
|
4
|
Pox_polyA_pol_N
|
Poxvirus poly(A) polymerase N-terminal domain
|
3
|
5
|
5
|
PPR
|
PPR repeat
|
2
|
4
|
2
|
PPR_2
|
PPR repeat family
|
2
|
26
|
18
|
PPV_E1_C
|
Papillomavirus helicase
|
3
|
24
|
23
|
PPV_E2_C
|
E2 (early) protein, C terminal
|
4
|
7
|
7
|
PQQ_2
|
PQQ-like domain
|
1
|
4
|
2
|
Pre-SET
|
Pre-SET motif
|
3
|
3
|
0
|
PriCT_1
|
Primase C terminal 1 (PriCT-1)
|
1
|
2
|
2
|
Prok-RING_1
|
Prokaryotic RING finger family 1
|
85
|
91
|
0
|
ProRS-C_1
|
Prolyl-tRNA synthetase, C-terminal
|
2
|
4
|
0
|
PseudoU_synth_1
|
tRNA pseudouridine synthase
|
3
|
20
|
15
|
PseudoU_synth_2
|
RNA pseudouridylate synthase
|
3
|
10
|
10
|
PspA_IM30
|
PspA/IM30 family
|
2
|
3
|
2
|
PTS-HPr
|
PTS HPr component phosphorylation site
|
5
|
13
|
0
|
PUA
|
PUA domain
|
16
|
18
|
15
|
PUF
|
Pumilio-family RNA binding repeat
|
36
|
341
|
324
|
Pur_DNA_glyco
|
Methylpurine-DNA glycosylase (MPG)
|
5
|
6
|
6
|
Put_DNA-bind_N
|
Putative DNA-binding protein N-terminus
|
3
|
8
|
8
|
Pyr_excise
|
Pyrimidine dimer DNA glycosylase
|
2
|
3
|
3
|
R-HINP1I
|
R.HinP1I restriction endonuclease
|
4
|
5
|
5
|
Rad4
|
Rad4 transglutaminase-like domain
|
3
|
3
|
3
|
RAI1
|
RAI1 like PD-(D/E)XK nuclease
|
4
|
6
|
6
|
RAMPs
|
RAMP superfamily
|
1
|
4
|
4
|
Rap1-DNA-bind
|
Rap1, DNA-binding
|
3
|
4
|
4
|
RapA_C
|
RNA polymerase recycling family C-terminal
|
1
|
2
|
0
|
Ras
|
Ras family
|
2
|
4
|
4
|
RCC1
|
Regulator of chromosome condensation (RCC1) repeat
|
1
|
10
|
0
|
RdRP_1
|
RNA dependent RNA polymerase
|
53
|
122
|
117
|
RdRP_3
|
Viral RNA dependent RNA polymerase
|
14
|
15
|
15
|
RdRP_4
|
Viral RNA-directed RNA-polymerase
|
7
|
8
|
8
|
RdRP_5
|
Reovirus RNA-dependent RNA polymerase lambda 3
|
4
|
4
|
4
|
RecA
|
recA bacterial DNA recombination protein
|
4
|
36
|
36
|
Recombinase
|
Recombinase
|
1
|
4
|
4
|
RecR
|
RecR protein
|
12
|
12
|
0
|
Regulator_TrmB
|
Archaeal transcriptional regulator TrmB
|
3
|
12
|
0
|
Rep_3
|
Initiator Replication protein
|
3
|
4
|
4
|
Rep_fac-A_3
|
Replication factor A protein 3
|
2
|
4
|
0
|
Rep_fac-A_C
|
Replication factor-A C terminal domain
|
3
|
5
|
5
|
Rep_N
|
Rep protein catalytic domain like
|
4
|
14
|
14
|
ResIII
|
Type III restriction enzyme, res subunit
|
7
|
11
|
9
|
Resolvase
|
Resolvase, N terminal domain
|
6
|
19
|
17
|
Response_reg
|
Response regulator receiver domain
|
2
|
4
|
0
|
RestrictionMunI
|
Type II restriction enzyme MunI
|
1
|
2
|
2
|
REV
|
REV protein (anti-repression trans-activator protein)
|
1
|
2
|
2
|
RE_Eco29kI
|
Eco29kI restriction endonuclease
|
2
|
16
|
16
|
RE_EcoO109I
|
Type II restriction endonuclease EcoO109I
|
1
|
2
|
2
|
RE_HindIII
|
HindIII restriction endonuclease
|
7
|
32
|
32
|
RE_NgoFVII
|
NgoFVII restriction endonuclease
|
2
|
4
|
4
|
RE_R_Pab1
|
R.Pab1 restriction endonuclease
|
1
|
2
|
2
|
RF-1
|
RF-1 domain
|
17
|
17
|
14
|
RFX_DNA_binding
|
RFX DNA-binding domain
|
1
|
2
|
2
|
RGS
|
Regulator of G protein signaling domain
|
2
|
2
|
0
|
Rhabdo_ncap
|
Rhabdovirus nucleocapsid protein
|
3
|
51
|
42
|
RHD
|
Rel homology domain (RHD)
|
27
|
68
|
68
|
RHH_1
|
Ribbon-helix-helix protein, copG family
|
3
|
24
|
24
|
Rho_N
|
Rho termination factor, N-terminal domain
|
7
|
37
|
0
|
Rho_RNA_bind
|
Rho termination factor, RNA-binding domain
|
7
|
39
|
30
|
Ribonuclease
|
ribonuclease
|
6
|
11
|
11
|
Ribonuclease_3
|
Ribonuclease III domain
|
1
|
1
|
0
|
Ribonuclease_P
|
Ribonuclease P
|
2
|
2
|
2
|
Ribonuclease_T2
|
Ribonuclease T2 family
|
1
|
1
|
1
|
Ribonucleas_3_3
|
Ribonuclease-III-like
|
12
|
25
|
14
|
Ribonuc_2-5A
|
Ribonuclease 2-5A
|
1
|
2
|
0
|
Ribosomal_60s
|
60s Acidic ribosomal protein
|
1
|
1
|
0
|
Ribosomal_L1
|
Ribosomal protein L1p/L10e family
|
154
|
161
|
148
|
Ribosomal_L10
|
Ribosomal protein L10
|
31
|
31
|
30
|
Ribosomal_L11
|
Ribosomal protein L11, RNA binding domain
|
248
|
252
|
221
|
Ribosomal_L11_N
|
Ribosomal protein L11, N-terminal domain
|
192
|
192
|
144
|
Ribosomal_L12
|
Ribosomal protein L7/L12 C-terminal domain
|
19
|
24
|
13
|
Ribosomal_L13
|
Ribosomal protein L13
|
412
|
412
|
373
|
Ribosomal_L13e
|
Ribosomal protein L13e
|
21
|
21
|
21
|
Ribosomal_L14
|
Ribosomal protein L14p/L23e
|
415
|
415
|
374
|
Ribosomal_L14e
|
Ribosomal protein L14
|
25
|
26
|
25
|
Ribosomal_L15e
|
Ribosomal L15
|
94
|
94
|
74
|
Ribosomal_L16
|
Ribosomal protein L16p/L10e
|
415
|
415
|
394
|
Ribosomal_L17
|
Ribosomal protein L17
|
316
|
316
|
303
|
Ribosomal_L18ae
|
Ribosomal L18ae/LX protein domain
|
22
|
22
|
4
|
Ribosomal_L18e
|
Ribosomal protein L18e/L15
|
411
|
505
|
442
|
Ribosomal_L18p
|
Ribosomal L18p/L5e family
|
425
|
425
|
407
|
Ribosomal_L18_c
|
Ribosomal L18 C-terminal region
|
43
|
43
|
42
|
Ribosomal_L19
|
Ribosomal protein L19
|
311
|
311
|
295
|
Ribosomal_L19e
|
Ribosomal protein L19e
|
96
|
96
|
71
|
Ribosomal_L2
|
Ribosomal Proteins L2, RNA binding domain
|
430
|
430
|
407
|
Ribosomal_L20
|
Ribosomal protein L20
|
315
|
315
|
303
|
Ribosomal_L21e
|
Ribosomal protein L21e
|
94
|
94
|
73
|
Ribosomal_L21p
|
Ribosomal prokaryotic L21 protein
|
311
|
311
|
300
|
Ribosomal_L22
|
Ribosomal protein L22p/L17e
|
420
|
420
|
378
|
Ribosomal_L22e
|
Ribosomal L22e protein family
|
21
|
21
|
4
|
Ribosomal_L23
|
Ribosomal protein L23
|
419
|
419
|
383
|
Ribosomal_L23eN
|
Ribosomal protein L23, N-terminal domain
|
21
|
21
|
4
|
Ribosomal_L24e
|
Ribosomal protein L24e
|
101
|
101
|
73
|
Ribosomal_L25p
|
Ribosomal L25p family
|
314
|
315
|
299
|
Ribosomal_L27
|
Ribosomal L27 protein
|
315
|
315
|
302
|
Ribosomal_L27e
|
Ribosomal L27e protein family
|
21
|
21
|
4
|
Ribosomal_L28
|
Ribosomal L28 family
|
275
|
275
|
274
|
Ribosomal_L28e
|
Ribosomal L28e protein family
|
4
|
4
|
4
|
Ribosomal_L29
|
Ribosomal L29 protein
|
415
|
415
|
379
|
Ribosomal_L29e
|
Ribosomal L29e protein family
|
21
|
21
|
4
|
Ribosomal_L2_C
|
Ribosomal Proteins L2, C-terminal domain
|
430
|
430
|
407
|
Ribosomal_L3
|
Ribosomal protein L3
|
432
|
438
|
412
|
Ribosomal_L30
|
Ribosomal protein L30p/L7e
|
426
|
426
|
404
|
Ribosomal_L30_N
|
Ribosomal L30 N-terminal domain
|
40
|
40
|
36
|
Ribosomal_L31
|
Ribosomal protein L31
|
201
|
201
|
137
|
Ribosomal_L31e
|
Ribosomal protein L31e
|
99
|
99
|
71
|
Ribosomal_L32e
|
Ribosomal protein L32
|
94
|
95
|
69
|
Ribosomal_L32p
|
Ribosomal L32p protein family
|
320
|
320
|
303
|
Ribosomal_L33
|
Ribosomal protein L33
|
313
|
313
|
291
|
Ribosomal_L34
|
Ribosomal protein L34
|
311
|
311
|
293
|
Ribosomal_L34e
|
Ribosomal protein L34e
|
23
|
23
|
5
|
Ribosomal_L35Ae
|
Ribosomal protein L35Ae
|
21
|
21
|
4
|
Ribosomal_L35p
|
Ribosomal protein L35
|
308
|
308
|
292
|
Ribosomal_L36
|
Ribosomal protein L36
|
259
|
259
|
244
|
Ribosomal_L36e
|
Ribosomal protein L36e
|
21
|
21
|
4
|
Ribosomal_L37ae
|
Ribosomal L37ae protein family
|
95
|
104
|
70
|
Ribosomal_L37e
|
Ribosomal protein L37e
|
94
|
94
|
74
|
Ribosomal_L38e
|
Ribosomal L38e protein family
|
21
|
21
|
4
|
Ribosomal_L39
|
Ribosomal L39 protein
|
95
|
95
|
75
|
Ribosomal_L4
|
Ribosomal protein L4/L1 family
|
437
|
437
|
411
|
Ribosomal_L40e
|
Ribosomal L40e family
|
22
|
23
|
4
|
Ribosomal_L41
|
Ribosomal protein L41
|
22
|
22
|
5
|
Ribosomal_L44
|
Ribosomal protein L44
|
96
|
104
|
77
|
Ribosomal_L5
|
Ribosomal protein L5
|
410
|
411
|
392
|
Ribosomal_L50
|
Ribosomal subunit 39S
|
2
|
2
|
1
|
Ribosomal_L5_C
|
ribosomal L5P family C-terminus
|
410
|
411
|
391
|
Ribosomal_L6
|
Ribosomal protein L6
|
427
|
854
|
802
|
Ribosomal_L6e
|
Ribosomal protein L6e
|
40
|
74
|
72
|
Ribosomal_L7Ae
|
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
|
210
|
260
|
237
|
Ribosomal_L9_C
|
Ribosomal protein L9, C-terminal domain
|
237
|
237
|
22
|
Ribosomal_L9_N
|
Ribosomal protein L9, N-terminal domain
|
270
|
270
|
255
|
Ribosomal_S10
|
Ribosomal protein S10p/S20e
|
452
|
459
|
442
|
Ribosomal_S11
|
Ribosomal protein S11
|
454
|
455
|
442
|
Ribosomal_S13
|
Ribosomal protein S13/S18
|
450
|
451
|
438
|
Ribosomal_S13_N
|
Ribosomal S13/S15 N-terminal domain
|
66
|
66
|
66
|
Ribosomal_S14
|
Ribosomal protein S14p/S29e
|
450
|
453
|
423
|
Ribosomal_S15
|
Ribosomal protein S15
|
459
|
461
|
446
|
Ribosomal_S16
|
Ribosomal protein S16
|
382
|
383
|
371
|
Ribosomal_S17
|
Ribosomal protein S17
|
451
|
452
|
439
|
Ribosomal_S17e
|
Ribosomal S17
|
66
|
66
|
66
|
Ribosomal_S18
|
Ribosomal protein S18
|
385
|
388
|
372
|
Ribosomal_S19
|
Ribosomal protein S19
|
453
|
453
|
442
|
Ribosomal_S19e
|
Ribosomal protein S19e
|
67
|
69
|
69
|
Ribosomal_S2
|
Ribosomal protein S2
|
451
|
504
|
486
|
Ribosomal_S20p
|
Ribosomal protein S20
|
379
|
380
|
370
|
Ribosomal_S21
|
Ribosomal protein S21
|
108
|
109
|
108
|
Ribosomal_S21e
|
Ribosomal protein S21e
|
62
|
62
|
23
|
Ribosomal_S24e
|
Ribosomal protein S24e
|
65
|
65
|
65
|
Ribosomal_S25
|
S25 ribosomal protein
|
64
|
64
|
64
|
Ribosomal_S26e
|
Ribosomal protein S26e
|
62
|
64
|
45
|
Ribosomal_S27
|
Ribosomal protein S27a
|
63
|
65
|
46
|
Ribosomal_S27e
|
Ribosomal protein S27
|
64
|
66
|
46
|
Ribosomal_S28e
|
Ribosomal protein S28e
|
66
|
66
|
49
|
Ribosomal_S30
|
Ribosomal protein S30
|
67
|
67
|
50
|
Ribosomal_S30AE
|
Sigma 54 modulation protein / S30EA ribosomal protein
|
9
|
9
|
9
|
Ribosomal_S3Ae
|
Ribosomal S3Ae family
|
64
|
64
|
64
|
Ribosomal_S3_C
|
Ribosomal protein S3, C-terminal domain
|
448
|
449
|
438
|
Ribosomal_S4
|
Ribosomal protein S4/S9 N-terminal domain
|
448
|
449
|
432
|
Ribosomal_S4e
|
Ribosomal family S4e
|
64
|
64
|
64
|
Ribosomal_S5
|
Ribosomal protein S5, N-terminal domain
|
453
|
454
|
439
|
Ribosomal_S5_C
|
Ribosomal protein S5, C-terminal domain
|
453
|
454
|
441
|
Ribosomal_S6
|
Ribosomal protein S6
|
385
|
387
|
371
|
Ribosomal_S6e
|
Ribosomal protein S6e
|
65
|
65
|
65
|
Ribosomal_S7
|
Ribosomal protein S7p/S5e
|
457
|
459
|
445
|
Ribosomal_S7e
|
Ribosomal protein S7e
|
62
|
62
|
62
|
Ribosomal_S8
|
Ribosomal protein S8
|
455
|
458
|
444
|
Ribosomal_S8e
|
Ribosomal protein S8e
|
64
|
64
|
64
|
Ribosomal_S9
|
Ribosomal protein S9/S16
|
452
|
453
|
440
|
Ribosomal_TL5_C
|
Ribosomal protein TL5, C-terminal domain
|
195
|
196
|
155
|
Ribosom_S12_S23
|
Ribosomal protein S12/S23
|
473
|
474
|
449
|
Ribos_L4_asso_C
|
60S ribosomal protein L4 C-terminal domain
|
38
|
38
|
34
|
Ricin_B_lectin
|
Ricin-type beta-trefoil lectin domain
|
1
|
2
|
0
|
RIG-I_C-RD
|
C-terminal domain of RIG-I
|
13
|
23
|
23
|
RIP
|
Ribosome inactivating protein
|
1
|
1
|
1
|
RLI
|
Possible Fer4-like domain in RNase L inhibitor, RLI
|
1
|
1
|
0
|
RMF
|
Ribosome modulation factor
|
2
|
2
|
2
|
RMMBL
|
RNA-metabolising metallo-beta-lactamase
|
3
|
8
|
5
|
RnaseA
|
Pancreatic ribonuclease
|
7
|
11
|
11
|
RNaseH_C
|
T4 RNase H, C terminal
|
1
|
1
|
1
|
RNase_E_G
|
Ribonuclease E/G family
|
1
|
4
|
4
|
RNase_H
|
RNase H
|
54
|
98
|
98
|
RNase_HII
|
Ribonuclease HII
|
5
|
5
|
5
|
RNase_H_2
|
RNase_H superfamily
|
18
|
19
|
14
|
RNase_PH
|
3' exoribonuclease family, domain 1
|
7
|
42
|
19
|
RNase_PH_C
|
3' exoribonuclease family, domain 2
|
7
|
30
|
7
|
RNase_T
|
Exonuclease
|
29
|
78
|
72
|
RNA_GG_bind
|
PHAX RNA-binding domain
|
1
|
1
|
1
|
RNA_ligase
|
RNA ligase
|
2
|
4
|
4
|
RNA_pol
|
DNA-dependent RNA polymerase
|
11
|
18
|
18
|
RNA_pol_A_bac
|
RNA polymerase Rpb3/RpoA insert domain
|
116
|
197
|
0
|
RNA_pol_A_CTD
|
Bacterial RNA polymerase, alpha chain C terminal domain
|
4
|
8
|
7
|
RNA_pol_L
|
RNA polymerase Rpb3/Rpb11 dimerisation domain
|
116
|
197
|
0
|
RNA_pol_L_2
|
RNA polymerase Rpb3/Rpb11 dimerisation domain
|
87
|
89
|
0
|
RNA_POL_M_15KD
|
RNA polymerases M/15 Kd subunit
|
84
|
86
|
0
|
RNA_pol_N
|
RNA polymerases N / 8 kDa subunit
|
87
|
89
|
0
|
RNA_pol_Rpb1_1
|
RNA polymerase Rpb1, domain 1
|
116
|
175
|
117
|
RNA_pol_Rpb1_2
|
RNA polymerase Rpb1, domain 2
|
116
|
143
|
119
|
RNA_pol_Rpb1_3
|
RNA polymerase Rpb1, domain 3
|
116
|
143
|
0
|
RNA_pol_Rpb1_4
|
RNA polymerase Rpb1, domain 4
|
116
|
143
|
3
|
RNA_pol_Rpb1_5
|
RNA polymerase Rpb1, domain 5
|
116
|
150
|
128
|
RNA_pol_Rpb1_6
|
RNA polymerase Rpb1, domain 6
|
85
|
87
|
0
|
RNA_pol_Rpb1_7
|
RNA polymerase Rpb1, domain 7
|
85
|
87
|
0
|
RNA_pol_Rpb2_1
|
RNA polymerase beta subunit
|
116
|
143
|
64
|
RNA_pol_Rpb2_2
|
RNA polymerase Rpb2, domain 2
|
116
|
152
|
35
|
RNA_pol_Rpb2_3
|
RNA polymerase Rpb2, domain 3
|
116
|
143
|
92
|
RNA_pol_Rpb2_4
|
RNA polymerase Rpb2, domain 4
|
87
|
89
|
0
|
RNA_pol_Rpb2_45
|
RNA polymerase beta subunit external 1 domain
|
29
|
54
|
0
|
RNA_pol_Rpb2_5
|
RNA polymerase Rpb2, domain 5
|
87
|
89
|
0
|
RNA_pol_Rpb2_6
|
RNA polymerase Rpb2, domain 6
|
116
|
143
|
108
|
RNA_pol_Rpb2_7
|
RNA polymerase Rpb2, domain 7
|
116
|
143
|
96
|
RNA_pol_Rpb4
|
RNA polymerase Rpb4
|
46
|
48
|
0
|
RNA_pol_Rpb5_C
|
RNA polymerase Rpb5, C-terminal domain
|
86
|
88
|
0
|
RNA_pol_Rpb5_N
|
RNA polymerase Rpb5, N-terminal domain
|
84
|
86
|
1
|
RNA_pol_Rpb6
|
RNA polymerase Rpb6
|
116
|
143
|
0
|
RNA_pol_Rpb8
|
RNA polymerase Rpb8
|
84
|
86
|
0
|
RNA_pol_Rpo13
|
RNA polymerase Rpo13 subunit HTH domain
|
2
|
2
|
0
|
RNA_replicase_B
|
RNA replicase, beta-chain
|
9
|
9
|
9
|
RNB
|
RNB domain
|
6
|
7
|
6
|
Rotavirus_VP1
|
Rotavirus VP1 structural protein
|
7
|
8
|
6
|
Rota_NSP3
|
Rotavirus non-structural protein NSP3
|
1
|
8
|
8
|
RPOL_N
|
DNA-directed RNA polymerase N-terminal
|
11
|
18
|
18
|
Rpp20
|
Rpp20 subunit of nuclear RNase MRP and P
|
1
|
1
|
1
|
RQC
|
RQC domain
|
6
|
9
|
9
|
RRF
|
Ribosome recycling factor
|
17
|
17
|
10
|
Rrf2
|
Transcriptional regulator
|
3
|
6
|
6
|
RRM_1
|
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
|
125
|
252
|
197
|
RRM_3
|
RNA binding motif
|
1
|
2
|
2
|
RRM_5
|
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
|
27
|
29
|
28
|
RRM_6
|
RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)
|
17
|
36
|
18
|
RrnaAD
|
Ribosomal RNA adenine dimethylase
|
4
|
4
|
3
|
rRNA_proc-arch
|
rRNA-processing arch domain
|
1
|
3
|
0
|
RS4NT
|
RS4NT (NUC023) domain
|
64
|
64
|
64
|
RTC
|
RNA 3'-terminal phosphate cyclase
|
1
|
2
|
2
|
RTC_insert
|
RNA 3'-terminal phosphate cyclase (RTC), insert domain
|
1
|
2
|
0
|
RTP
|
Replication terminator protein
|
4
|
10
|
10
|
Runt
|
Runt domain
|
15
|
26
|
26
|
RusA
|
Endodeoxyribonuclease RusA
|
1
|
4
|
2
|
RuvA_C
|
RuvA, C-terminal domain
|
2
|
8
|
4
|
RuvA_N
|
RuvA N terminal domain
|
2
|
8
|
0
|
RuvC
|
Crossover junction endodeoxyribonuclease RuvC
|
1
|
2
|
2
|
RVT_1
|
Reverse transcriptase (RNA-dependent DNA polymerase)
|
58
|
147
|
89
|
RVT_connect
|
Reverse transcriptase connection domain
|
31
|
100
|
69
|
RVT_thumb
|
Reverse transcriptase thumb domain
|
31
|
100
|
46
|
S1
|
S1 RNA binding domain
|
53
|
58
|
3
|
S10_plectin
|
Plectin/S10 domain
|
62
|
62
|
62
|
S4
|
S4 domain
|
453
|
514
|
499
|
SAD_SRA
|
SAD/SRA domain
|
19
|
40
|
37
|
SAM_2
|
SAM domain (Sterile alpha motif)
|
3
|
3
|
3
|
SAP
|
SAP domain
|
4
|
8
|
8
|
Sas10_Utp3
|
Sas10/Utp3/C1D family
|
1
|
1
|
0
|
SASP
|
Small, acid-soluble spore proteins, alpha/beta type
|
1
|
3
|
3
|
SbcCD_C
|
Putative exonuclease SbcCD, C subunit
|
1
|
4
|
0
|
SBP_bac_1
|
Bacterial extracellular solute-binding protein
|
1
|
1
|
0
|
Sec61_beta
|
Sec61beta family
|
7
|
7
|
0
|
SecE
|
SecE/Sec61-gamma subunits of protein translocation complex
|
9
|
9
|
0
|
SecG
|
Preprotein translocase SecG subunit
|
2
|
2
|
0
|
SecM
|
Secretion monitor precursor protein (SecM)
|
1
|
1
|
1
|
SecY
|
SecY translocase
|
10
|
10
|
10
|
SelB-wing_2
|
Elongation factor SelB, winged helix
|
2
|
6
|
6
|
SelB-wing_3
|
Elongation factor SelB, winged helix
|
4
|
11
|
8
|
SeqA
|
SeqA protein
|
4
|
13
|
9
|
Seryl_tRNA_N
|
Seryl-tRNA synthetase N-terminal domain
|
1
|
2
|
1
|
SET
|
SET domain
|
3
|
3
|
0
|
SH2
|
SH2 domain
|
2
|
3
|
0
|
SHS2_Rpb7-N
|
SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397
|
47
|
49
|
0
|
Sigma54_DBD
|
Sigma-54, DNA binding domain
|
2
|
2
|
2
|
Sigma70_ner
|
Sigma-70, non-essential region
|
4
|
19
|
0
|
Sigma70_r1_2
|
Sigma-70 factor, region 1.2
|
23
|
41
|
40
|
Sigma70_r2
|
Sigma-70 region 2
|
26
|
45
|
44
|
Sigma70_r3
|
Sigma-70 region 3
|
22
|
38
|
30
|
Sigma70_r4
|
Sigma-70, region 4
|
26
|
45
|
28
|
Sigma70_r4_2
|
Sigma-70, region 4
|
1
|
2
|
2
|
SLBP_RNA_bind
|
Histone RNA hairpin-binding protein RNA-binding domain
|
6
|
9
|
9
|
SLIDE
|
SLIDE
|
1
|
1
|
0
|
SmpB
|
SmpB protein
|
9
|
14
|
11
|
SNF2_N
|
SNF2 family N-terminal domain
|
2
|
4
|
2
|
Spo0A_C
|
Sporulation initiation factor Spo0A C terminal
|
1
|
4
|
4
|
SRC-1
|
Steroid receptor coactivator
|
1
|
3
|
0
|
SRF-TF
|
SRF-type transcription factor (DNA-binding and dimerisation domain)
|
11
|
36
|
34
|
SRP-alpha_N
|
Signal recognition particle, alpha subunit, N-terminal
|
1
|
1
|
1
|
SRP14
|
Signal recognition particle 14kD protein
|
6
|
10
|
7
|
SRP19
|
SRP19 protein
|
14
|
18
|
17
|
SRP54
|
SRP54-type protein, GTPase domain
|
12
|
24
|
8
|
SRP54_N
|
SRP54-type protein, helical bundle domain
|
12
|
24
|
1
|
SRP9-21
|
Signal recognition particle 9 kDa protein (SRP9)
|
6
|
8
|
5
|
SRPRB
|
Signal recognition particle receptor beta subunit
|
1
|
1
|
0
|
SRP_SPB
|
Signal peptide binding domain
|
30
|
37
|
35
|
SSB
|
Single-strand binding protein family
|
4
|
14
|
14
|
STAT_alpha
|
STAT protein, all-alpha domain
|
2
|
3
|
0
|
STAT_bind
|
STAT protein, DNA binding domain
|
2
|
3
|
3
|
Stm1_N
|
Stm1
|
34
|
34
|
17
|
SUI1
|
Translation initiation factor SUI1
|
12
|
12
|
12
|
Sulf_coat_C
|
Sulfolobus virus coat protein C terminal
|
1
|
58
|
58
|
SUV3_C
|
Mitochondrial degradasome RNA helicase subunit C terminal
|
1
|
1
|
0
|
T-box
|
T-box
|
4
|
8
|
7
|
T4-Gluco-transf
|
Bacteriophage T4 beta-glucosyltransferase
|
4
|
8
|
5
|
Tap-RNA_bind
|
Tap, RNA-binding
|
1
|
2
|
2
|
Taq-exonuc
|
Taq polymerase, exonuclease
|
48
|
48
|
21
|
TaqI_C
|
TaqI-like C-terminal specificity domain
|
9
|
16
|
16
|
TatD_DNase
|
TatD related DNase
|
1
|
1
|
1
|
TBP
|
Transcription factor TFIID (or TATA-binding protein, TBP)
|
29
|
100
|
100
|
TCR
|
Tesmin/TSO1-like CXC domain, cysteine-rich domain
|
1
|
1
|
1
|
TEBP_beta
|
Telomere-binding protein beta subunit (TEBP beta)
|
14
|
14
|
14
|
Telomerase_RBD
|
Telomerase ribonucleoprotein complex - RNA binding domain
|
2
|
3
|
2
|
Tenui_N
|
Tenuivirus/Phlebovirus nucleocapsid protein
|
4
|
70
|
70
|
Ter
|
DNA replication terminus site-binding protein (Ter protein)
|
8
|
8
|
8
|
TetR_C
|
Tetracyclin repressor, C-terminal all-alpha domain
|
2
|
5
|
0
|
TetR_C_5
|
QacR-like protein, C-terminal region
|
1
|
4
|
0
|
TetR_N
|
Bacterial regulatory proteins, tetR family
|
10
|
53
|
49
|
Tet_JBP
|
Oxygenase domain of the 2OGFeDO superfamily
|
4
|
5
|
5
|
TFIIA
|
Transcription factor IIA, alpha/beta subunit
|
4
|
8
|
4
|
TFIIA_gamma_C
|
Transcription initiation factor IIA, gamma subunit
|
4
|
4
|
0
|
TFIIA_gamma_N
|
Transcription initiation factor IIA, gamma subunit, helical domain
|
4
|
4
|
0
|
TFIIB
|
Transcription factor TFIIB repeat
|
7
|
21
|
17
|
TFIIF_alpha
|
Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
|
2
|
2
|
0
|
TFIIF_beta
|
Transcription initiation factor IIF, beta subunit
|
2
|
2
|
0
|
TFIIS_C
|
Transcription factor S-II (TFIIS)
|
84
|
89
|
1
|
TFIIS_M
|
Transcription factor S-II (TFIIS), central domain
|
6
|
6
|
0
|
TF_Zn_Ribbon
|
TFIIB zinc-binding
|
3
|
3
|
3
|
TGS
|
TGS domain
|
3
|
3
|
0
|
TGT
|
Queuine tRNA-ribosyltransferase
|
3
|
10
|
6
|
TGT_C1
|
C1 domain of tRNA-guanine transglycosylase dimerisation
|
1
|
2
|
2
|
TGT_C2
|
Patch-forming domain C2 of tRNA-guanine transglycosylase
|
1
|
2
|
2
|
ThaI
|
Restriction endonuclease ThaI
|
1
|
2
|
2
|
THAP
|
THAP domain
|
3
|
3
|
3
|
Thg1
|
tRNAHis guanylyltransferase
|
2
|
8
|
2
|
Thg1C
|
Thg1 C terminal domain
|
2
|
8
|
6
|
ThiI
|
Thiamine biosynthesis protein (ThiI)
|
3
|
6
|
5
|
Thioredoxin
|
Thioredoxin
|
17
|
19
|
2
|
Thrombin_light
|
Thrombin light chain
|
10
|
11
|
0
|
THUMP
|
THUMP domain
|
3
|
6
|
6
|
TIG
|
IPT/TIG domain
|
20
|
40
|
11
|
TilS
|
TilS substrate binding domain
|
1
|
2
|
2
|
TilS_C
|
TilS substrate C-terminal domain
|
1
|
2
|
2
|
Tim44
|
Tim44-like domain
|
2
|
2
|
1
|
TMF_TATA_bd
|
TATA element modulatory factor 1 TATA binding
|
1
|
1
|
1
|
TMV_coat
|
Virus coat protein (TMV like)
|
11
|
11
|
11
|
Tna_leader
|
Tryptophanese operon leader peptide
|
1
|
1
|
1
|
Tnp_DNA_bind
|
Transposase DNA-binding
|
4
|
8
|
8
|
TNV_CP
|
Satellite tobacco necrosis virus coat protein
|
1
|
1
|
1
|
Tombus_P19
|
Tombusvirus P19 core protein
|
4
|
8
|
8
|
Topoisom_bac
|
DNA topoisomerase
|
8
|
13
|
13
|
Topoisom_I
|
Eukaryotic DNA topoisomerase I, catalytic core
|
20
|
20
|
19
|
Topoisom_I_N
|
Eukaryotic DNA topoisomerase I, DNA binding fragment
|
16
|
16
|
16
|
Topo_C_assoc
|
C-terminal topoisomerase domain
|
16
|
16
|
15
|
Toprim
|
Toprim domain
|
38
|
82
|
82
|
Toprim_4
|
Toprim domain
|
1
|
2
|
0
|
Toprim_N
|
DNA primase catalytic core, N-terminal domain
|
1
|
2
|
2
|
Tower
|
Tower
|
1
|
1
|
1
|
ToxN_toxin
|
Toxin ToxN, type III toxin-antitoxin system
|
3
|
10
|
10
|
TPR_1
|
Tetratricopeptide repeat
|
3
|
3
|
0
|
TPR_11
|
TPR repeat
|
3
|
6
|
6
|
TPR_12
|
Tetratricopeptide repeat
|
4
|
5
|
0
|
TRAM
|
TRAM domain
|
1
|
2
|
2
|
Translin
|
Translin family
|
1
|
24
|
12
|
Transposase_1
|
Transposase (partial DDE domain)
|
4
|
8
|
8
|
Trans_reg_C
|
Transcriptional regulatory protein, C terminal
|
6
|
33
|
11
|
Tra_M
|
TraM protein, DNA-binding
|
1
|
8
|
8
|
Trigger_N
|
Bacterial trigger factor protein (TF)
|
3
|
3
|
2
|
TrmB
|
Sugar-specific transcriptional regulator TrmB
|
3
|
12
|
12
|
tRNA-synt_1
|
tRNA synthetases class I (I, L, M and V)
|
20
|
49
|
41
|
tRNA-synt_1b
|
tRNA synthetases class I (W and Y)
|
6
|
20
|
20
|
tRNA-synt_1c
|
tRNA synthetases class I (E and Q), catalytic domain
|
27
|
37
|
36
|
tRNA-synt_1c_C
|
tRNA synthetases class I (E and Q), anti-codon binding domain
|
18
|
18
|
17
|
tRNA-synt_1d
|
tRNA synthetases class I (R)
|
4
|
10
|
6
|
tRNA-synt_1e
|
tRNA synthetases class I (C) catalytic domain
|
1
|
1
|
1
|
tRNA-synt_1g
|
tRNA synthetases class I (M)
|
11
|
16
|
7
|
tRNA-synt_1_2
|
Leucyl-tRNA synthetase, Domain 2
|
12
|
18
|
18
|
tRNA-synt_2
|
tRNA synthetases class II (D, K and N)
|
7
|
19
|
10
|
tRNA-synt_2b
|
tRNA synthetase class II core domain (G, H, P, S and T)
|
6
|
19
|
16
|
tRNA-synt_2c
|
tRNA synthetases class II (A)
|
2
|
4
|
2
|
tRNA-synt_2d
|
tRNA synthetases class II core domain (F)
|
3
|
8
|
8
|
tRNA_anti-codon
|
OB-fold nucleic acid binding domain
|
19
|
38
|
35
|
tRNA_bind
|
Putative tRNA binding domain
|
2
|
4
|
0
|
tRNA_int_endo
|
tRNA intron endonuclease, catalytic C-terminal domain
|
1
|
4
|
4
|
tRNA_int_endo_N
|
tRNA intron endonuclease, N-terminal domain
|
1
|
4
|
0
|
tRNA_m1G_MT
|
tRNA (Guanine-1)-methyltransferase
|
3
|
6
|
6
|
tRNA_Me_trans
|
tRNA methyl transferase
|
3
|
5
|
5
|
tRNA_NucTransf2
|
tRNA nucleotidyltransferase, second domain
|
34
|
68
|
66
|
tRNA_SAD
|
Threonyl and Alanyl tRNA synthetase second additional domain
|
3
|
5
|
1
|
tRNA_U5-meth_tr
|
tRNA (Uracil-5-)-methyltransferase
|
2
|
4
|
4
|
TROVE
|
TROVE domain
|
2
|
4
|
4
|
TrpBP
|
Tryptophan RNA-binding attenuator protein
|
6
|
132
|
66
|
Trp_repressor
|
Trp repressor protein
|
4
|
16
|
16
|
TruB-C_2
|
Pseudouridine synthase II TruB, C-terminal
|
2
|
2
|
1
|
TruB_N
|
TruB family pseudouridylate synthase (N terminal domain)
|
17
|
24
|
22
|
TrwC
|
TrwC relaxase
|
8
|
11
|
11
|
Trypsin
|
Trypsin
|
10
|
11
|
11
|
Tudor-knot
|
RNA binding activity-knot of a chromodomain
|
1
|
2
|
2
|
Tymo_coat
|
Tymovirus coat protein
|
3
|
9
|
5
|
Tyr-DNA_phospho
|
Tyrosyl-DNA phosphodiesterase
|
8
|
16
|
16
|
T_Ag_DNA_bind
|
Origin of replication binding protein
|
7
|
20
|
20
|
U1snRNP70_N
|
U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
|
3
|
7
|
5
|
UBA
|
UBA/TS-N domain
|
9
|
9
|
0
|
UDG
|
Uracil DNA glycosylase superfamily
|
33
|
52
|
46
|
UPF1_Zn_bind
|
RNA helicase (UPF2 interacting domain)
|
1
|
1
|
0
|
UQ_con
|
Ubiquitin-conjugating enzyme
|
1
|
2
|
1
|
UTRA
|
UTRA domain
|
1
|
2
|
0
|
UvdE
|
UV-endonuclease UvdE
|
1
|
1
|
1
|
UVR
|
UvrB/uvrC motif
|
2
|
4
|
0
|
UvrB
|
Ultra-violet resistance protein B
|
4
|
6
|
0
|
UvrD-helicase
|
UvrD/REP helicase N-terminal domain
|
17
|
36
|
36
|
UvrD_C
|
UvrD-like helicase C-terminal domain
|
17
|
35
|
35
|
UvrD_C_2
|
UvrD-like helicase C-terminal domain
|
5
|
10
|
6
|
V-set
|
Immunoglobulin V-set domain
|
23
|
62
|
34
|
Val_tRNA-synt_C
|
Valyl tRNA synthetase tRNA binding arm
|
2
|
4
|
4
|
Viral_coat
|
Viral coat protein (S domain)
|
10
|
360
|
197
|
Viral_helicase1
|
Viral (Superfamily 1) RNA helicase
|
1
|
4
|
4
|
VirDNA-topo-I_N
|
Viral DNA topoisomerase I, N-terminal
|
3
|
3
|
3
|
VP40
|
Matrix protein VP40
|
2
|
9
|
9
|
VRR_NUC
|
VRR-NUC domain
|
9
|
18
|
11
|
Vsr
|
DNA mismatch endonuclease Vsr
|
2
|
2
|
2
|
VWA
|
von Willebrand factor type A domain
|
2
|
2
|
2
|
WD40
|
WD domain, G-beta repeat
|
67
|
342
|
198
|
WGR
|
WGR domain
|
4
|
8
|
8
|
WHIM1
|
WSTF, HB1, Itc1p, MBD9 motif 1
|
1
|
1
|
0
|
Whirly
|
Whirly transcription factor
|
3
|
3
|
3
|
WRKY
|
WRKY DNA -binding domain
|
1
|
1
|
1
|
XPA_C
|
XPA protein C-terminus
|
1
|
2
|
2
|
XPC-binding
|
XPC-binding domain
|
3
|
3
|
0
|
XPG_I
|
XPG I-region
|
12
|
21
|
7
|
XPG_N
|
XPG N-terminal domain
|
12
|
22
|
19
|
Xpo1
|
Exportin 1-like protein
|
2
|
4
|
2
|
XRN_N
|
XRN 5'-3' exonuclease N-terminus
|
1
|
1
|
1
|
Y1_Tnp
|
Transposase IS200 like
|
11
|
27
|
27
|
YqaJ
|
YqaJ-like viral recombinase domain
|
3
|
9
|
9
|
YTH
|
YT521-B-like domain
|
4
|
9
|
9
|
z-alpha
|
Adenosine deaminase z-alpha domain
|
14
|
40
|
31
|
zf-C2H2
|
Zinc finger, C2H2 type
|
8
|
22
|
21
|
zf-C2HC
|
Zinc finger, C2HC type
|
2
|
3
|
3
|
zf-C3HC4
|
Zinc finger, C3HC4 type (RING finger)
|
1
|
4
|
0
|
zf-C4
|
Zinc finger, C4 type (two domains)
|
59
|
138
|
138
|
zf-CCCH
|
Zinc finger C-x8-C-x5-C-x3-H type (and similar)
|
3
|
8
|
5
|
zf-CCCH_2
|
Zinc finger C-x8-C-x5-C-x3-H type
|
1
|
2
|
1
|
zf-CCHC
|
Zinc knuckle
|
24
|
39
|
39
|
zf-CXXC
|
CXXC zinc finger domain
|
14
|
15
|
15
|
zf-Di19
|
Drought induced 19 protein (Di19), zinc-binding
|
1
|
2
|
2
|
zf-FPG_IleRS
|
Zinc finger found in FPG and IleRS
|
66
|
72
|
69
|
zf-H2C2_2
|
Zinc-finger double domain
|
43
|
111
|
111
|
zf-His_Me_endon
|
Zinc-binding loop region of homing endonuclease
|
7
|
16
|
16
|
zf-met
|
Zinc-finger of C2H2 type
|
1
|
1
|
1
|
zf-PARP
|
Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
|
9
|
32
|
32
|
zf-primase
|
Primase zinc finger
|
1
|
1
|
0
|
zf-RanBP
|
Zn-finger in Ran binding protein and others
|
1
|
1
|
1
|
zf-rbx1
|
RING-H2 zinc finger
|
2
|
3
|
0
|
zf-ribbon_3
|
zinc-ribbon domain
|
1
|
1
|
1
|
zf-RNPHF
|
RNPHF zinc finger
|
1
|
1
|
0
|
zf-TAZ
|
TAZ zinc finger
|
1
|
1
|
0
|
zf-U1
|
U1 zinc finger
|
2
|
8
|
4
|
zinc_ribbon_2
|
zinc-ribbon domain
|
1
|
2
|
2
|
Zn_clus
|
Fungal Zn(2)-Cys(6) binuclear cluster domain
|
12
|
28
|
28
|
Zn_ribbon_recom
|
Recombinase zinc beta ribbon domain
|
1
|
4
|
4
|
|